Evidence map›Paper›PMID 29262616›Full record

ArticleOncotarget2017

Loss of digestive organ expansion factor (

Neeraj K Aryal, Amanda R Wasylishen, Vinod Pant, Maurisa Riley-Croce, Guillermina Lozano

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Article
  8. Daxx Functions Are p53-IndependentMolecular cancer research : MCR · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neeraj K AryalDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Amanda R WasylishenDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Vinod PantDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Maurisa Riley-CroceDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Guillermina LozanoDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
PATHWAY OF TUMOR SUPPRESSIONR01CA047296 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GUILLERMINA LOZANO · 1993 to 2026
$8.0M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA047296
6 · The paper itself

Abstract

Increased levels of inhibitors of the p53 tumor suppressor such as Mdm2 and Mdm4 drive tumor development and thus serve as targets for therapeutic intervention. Recently, digestive organ expansion factor (Diexf) has been identified as a novel inhibitor of p53 in zebrafish. Here, we address the potential role of Diexf as a regulator of the p53 pathway in mammals by generating

Indexed as

CRISPR/Cas9Def-Capn3 nucleolar pathwayMdm4 co-amplificationmouse modelribosome small subunit processome

Identifiers

PMID29262616
PMCPMC5732782

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.