Evidence map›Paper›PMID 29262326›Full record

ArticleCell reports2017

HIV-Specific CD8

Morgan A Reuter, Perla M Del Rio Estrada, Marcus Buggert, Constantinos Petrovas, Sara Ferrando-Martinez, Son Nguyen, Alberto Sada Japp, Yuria Ablanedo-Terrazas, Amaranta Rivero-Arrieta, Leticia Kuri-Cervantes and 8 more

Abstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
  2. Renaissance of antiviral CD8Nature reviews. Immunology · 2026
    Review
  3. CD8MedComm · 2026
    Review
  4. HIV controllers, lessons learnt from the lymphoid tissues.Current opinion in HIV and AIDS · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Therapeutic CD8Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Cell therapies for viral diseases: a new frontier.Seminars in immunopathology · 2025
    Review
  16. Article
  17. Distinct SIV-specific CD8Nature immunology · 2024
    Article
  18. Article
  19. Spatial transcriptomics andFrontiers in immunology · 2024
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Morgan A ReuterDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Perla M Del Rio EstradaDepartamento de Investigación en Enfermedades Infecciosas, INER, Mexico City, Mexico.
Marcus BuggertDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Constantinos PetrovasImmunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
Sara Ferrando-MartinezImmunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
Son NguyenDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alberto Sada JappDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Yuria Ablanedo-TerrazasDepartamento de Investigación en Enfermedades Infecciosas, INER, Mexico City, Mexico.
Amaranta Rivero-ArrietaDepartamento de Investigación en Enfermedades Infecciosas, INER, Mexico City, Mexico.
Leticia Kuri-CervantesDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Heidi M GunzelmanDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Emma GostickInstitute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.
David A PriceInstitute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.
Richard A KoupImmunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
Ali NajiDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David H CanadayDivision of Infectious Diseases and HIV Medicine, Case Western Reserve University, Cleveland, OH, USA; Division of Geriatric Research, Louis Stokes VA Medical Center, Cleveland, OH, USA.
Gustavo Reyes-TeránDepartamento de Investigación en Enfermedades Infecciosas, INER, Mexico City, Mexico.
Michael R BettsDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: betts@pennmedicine.upenn.edu.

Funding

T cell functionality and control of HIV infectionR01AI076066 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R · 2008 to 2017
$4.6M
Viral control mechanisms of HIV-specific T cells in HIV-infected lymph nodeR01AI118694 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R · 2015 to 2019
$3.3M
CD4+ T and B cell mechanisms of influenza vaccine non-responsiveness in older aduR01AI108972 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BETTS, MICHAEL R, CANADAY, DAVID H · 2014 to 2018
$2.5M
NIAID NIH HHS R01 AI076066NIAID NIH HHS R01 AI108972NIAID NIH HHS R01 AI118694Wellcome Trust
6 · The paper itself

Abstract

Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8

Indexed as

Cytotoxicity, ImmunologicCD8-Positive T-LymphocytesCells, CulturedHIV InfectionsHumansImmunologic MemoryLymphoid TissueReceptors, CXCR5Receptors, CXCR5CD8(+) T cellscytotoxicityHIVlymphoid tissue

Identifiers

PMID29262326
PMCPMC5764192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.