ArticlePublic health reports (Washington, D.C. : 1974)
Excess Clinical Comorbidity Among HIV-Infected Patients Accessing Primary Care in US Community Health Centers.
Article in Public health reports (Washington, D.C. : 1974). The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Higher cardiovascular disease risks in people living with HIV: A systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Association between HIV infection and hypertension: a global systematic review and meta-analysis of cross-sectional studies.BMC medicine · 2021Pooled it
- Barriers and mitigating strategies to routine HIV screening in emergency departments: A national qualitative study.HIV medicine · 2026Article
- Study of Bone Marrow Findings in Human Immunodeficiency Virus (HIV) Positive Patients in a Tertiary Care Hospital.Cardiovascular & hematological disorders drug targets · 2026Article
- Anticipated Protection Overcomes Vaccine Hesitancy and Mistrust Among Women Enrolled in the DC MACS/WIHS Combined Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Testing the Efficacy of 2 Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Differences in emergency department visit characteristics and resource utilization for persons with human immunodeficiency virus, 2018-2019 compared with 2009-2010.BMC emergency medicine · 2025Article
- Sequelae of Immunocompromised Host Pneumonia.Clinics in chest medicine · 2025Review
- Comorbidities in people living with HIV/AIDS and their impact on outpatient dental care.Brazilian oral research · 2025Observational
- Cost analysis of adding hypertension and diabetes management into routine HIV care in Mbarara and Ibanda districts, Uganda.BMC health services research · 2024Article
- The Intersection of HIV and Pulmonary Vascular Health: From HIV Evolution to Vascular Cell Types to Disease Mechanisms.Journal of vascular diseases · 2024Article
- Does the Quality of Behavior Change Counseling in Routine HIV Care Vary According to Topic and Demand?AIDS and behavior · 2023Article
- Article
- Hypertension and associated factors in HIV-infected patients receiving antiretroviral treatment in Burundi: a cross-sectional study.Scientific reports · 2022Article
- Risk of Severe COVID-19 Disease and the Pandemic's Impact on Service Utilization Among a Longitudinal Cohort of Persons with HIV-Washington, DC.AIDS and behavior · 2022Article
- A Heavy Burden: Preexisting Physical and Psychiatric Comorbidities and Differential Increases Among Male and Female Participants After Initiating Antiretroviral Therapy in the HIV Outpatient Study, 2008-2018.AIDS research and human retroviruses · 2022Article
- Observational
- Beyond viral suppression: Quality of life among stable ART clients in a differentiated service delivery intervention in Tanzania.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Disability-adjusted life years associated with chronic comorbidities among people living with and without HIV: Estimating health burden in British Columbia, Canada.PLOS global public health · 2022Article
- Redefining therapeutic success in HIV patients: an expert view.The Journal of antimicrobial chemotherapy · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 8 institutions in 1 country.
Funding
Abstract
objectivesAs the life expectancy of people infected with human immunodeficiency virus (HIV) infection has increased, the spectrum of illness has evolved. We evaluated whether people living with HIV accessing primary care in US community health centers had higher morbidity compared with HIV-uninfected patients receiving care at the same sites.
methodsWe compared data from electronic health records for 12 837 HIV-infected and 227 012 HIV-uninfected patients to evaluate the relative prevalence of diabetes mellitus, hypertension, chronic kidney disease, dyslipidemia, and malignancies by HIV serostatus. We used multivariable logistic regression to evaluate differences. Participants were patients aged ≥18 who were followed for ≥3 years (from January 2006 to December 2016) in 1 of 17 community health centers belonging to the Community Health Applied Research Network.
resultsNearly two-thirds of HIV-infected and HIV-uninfected patients lived in poverty. Compared with HIV-uninfected patients, HIV-infected patients were significantly more likely to be diagnosed and/or treated for diabetes (odds ratio [OR] = 1.18; 95% confidence interval [CI], 1.22-1.41), hypertension (OR = 1.38; 95% CI, 1.31-1.46), dyslipidemia (OR = 2.30; 95% CI, 2.17-2.43), chronic kidney disease (OR = 4.75; 95% CI, 4.23-5.34), lymphomas (OR = 4.02; 95% CI, 2.86-5.67), cancers related to human papillomavirus (OR = 5.05; 95% CI, 3.77-6.78), or other cancers (OR = 1.25; 95% CI, 1.10-1.42). The prevalence of stroke was higher among HIV-infected patients (OR = 1.32; 95% CI, 1.06-1.63) than among HIV-uninfected patients, but the prevalence of myocardial infarction or coronary artery disease did not differ between the 2 groups.
conclusionsAs HIV-infected patients live longer, the increasing burden of noncommunicable diseases may complicate their clinical management, requiring primary care providers to be trained in chronic disease management for this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.