ArticlePloS one2017
Comparing the self-perceived quality of life of multimorbid patients and the general population using the EQ-5D-3L.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Everyday Lives of Middle-Aged Persons with Multimorbidity: A Mixed Methods Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Pooled it
- Effect of the OPTIMAL programme on self-management of multimorbidity in primary care: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care - A cluster-randomised clinical trial.BMC geriatrics · 2020Trial
- The association between multimorbidity and needs-based quality of life in primary care: a cross-sectional questionnaire study.Scandinavian journal of primary health care · 2026Article
- Article
- The Role of Advanced Practice Nurses in the Care of Multimorbid and Complex Chronically Ill Young and Middle-Aged Adults in Hospital Settings-Perspectives on Experience of APNs: A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- Impact of multimorbidity on change in quality of life in a multi-ethnic Asian population: a longitudinal study.Health and quality of life outcomes · 2026Article
- Analysing the impact of complex multimorbidity on health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Impact of Comorbidity Clusters on Quality of Life in Chronic Heart Failure.Vascular health and risk management · 2026Article
- Assessing the quality of life in patients with complex chronic conditions: Cronimad study.BMC geriatrics · 2025Article
- Home Caregivers of Elderly People: Perceptions and Quality of Life.Geriatrics (Basel, Switzerland) · 2025Article
- Evaluating the effects of surgery on health-related quality of life in asymptomatic meningioma patients.Neuro-oncology practice · 2025Article
- Article
- Factors associated with self-management in older adults with multiple chronic conditions: a qualitative study.Frontiers in public health · 2024Article
- Sensitivity analysis of EQ-5D-3L index scores in terms of discriminative and known-groups validity in SLE: introducing Adequate Health State.Rheumatology (Oxford, England) · 2023Article
- Goals of older hospitalized patients with multimorbidity.European geriatric medicine · 2023Article
- Multimorbidity and Quality of Life: The Mediating Role of ADL, IADL, Loneliness, and Depressive Symptoms.Innovation in aging · 2023Article
- Healthcare Costs and Health-Related Quality of Life in Older Multimorbid Patients After Hospitalization.Health services insights · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess and compare the self-perceived Health Related Quality of Life (HRQoL) of multimorbid patients and the general population using health utilities (HU) and visual analogue scale (VAS) methods.
methodsWe analyzed data (n = 888) from a national, cross-sectional Swiss study of multimorbid patients recruited in primary care settings. Self-perceived HRQoL was assessed using the EQ-5D-3L instrument, composed of 1) a questionnaire on the five dimensions of mobility, self-care, usual activities, pain/discomfort, and anxiety/depression (EQ-5D dimensions), and 2) a 0-100 (0 = worst- and 100 = best-imaginable health status) VAS. We described the EQ-5D dimensions and VAS and computed HU using a standard pan-European value set. HU and VAS are the two components of the overall HRQoL assessment. We examined the proportions of multimorbid patients reporting problems (moderate/severe) in each EQ-5D dimension, corresponding proportions without problems, and mean HU and VAS values across patient characteristics. To test differences between subgroups, we used chi-square tests for dichotomous outcomes and T-tests (ANOVA if more than two groups) for continuous outcomes. Finally, we compared observed and predicted HU and VAS values.
resultsAll 888 participants answered every EQ-5D item. Mean (SD) HU and VAS values were 0.70 (0.18) and 63.2 (19.2), respectively. HU and VAS were considerably and significantly lower in multimorbid patients than in the general population and were also lower in multimorbid patients below 60 years old and in women. Differences between observed and predicted means (SD) were -0.07 (0.18) for HU and -11.8 (20.3) for VAS.
conclusionsSelf-perceived HRQoL is considerably and significantly affected by multimorbidity. More attention should be given to developing interventions that improve the HRQoL of multimorbid patients, particularly women and those aged below 60 years old.
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