Evidence map›Paper›PMID 29261169›Full record

ArticleMolecules (Basel, Switzerland)2017

Access to New Cytotoxic Quinone-Amino Acid Conjugates Linked through A Vinylic Spacer from 2-Acylnaphthoquinones and Methyl 3-Aminocrotonate.

Jaime A Valderrama, Joel Garrido, Virginia Delgado, Julio Benites, Cristina Theoduloz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jaime A ValderramaInstituto de Ciencias Exactas y Naturales (ICEN), Universidad Arturo Prat Casilla 121, Iquique 1100000, Chile. jaimeadolfov@gmail.com.
Joel GarridoQuímica y Farmacia, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Casilla 121, Iquique 1100000, Chile. goejizz@gmail.com.
Virginia DelgadoFacultad de Química, Pontificia Universidad Católica de Chile, Casilla 306, Santiago 6094411, Chile. vcdelgad@uc.cl.
Julio BenitesInstituto de Ciencias Exactas y Naturales (ICEN), Universidad Arturo Prat Casilla 121, Iquique 1100000, Chile. juliob@unap.cl.ORCID 0000-0002-8562-0078
Cristina TheodulozFacultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. ctheodul@utalca.cl.
Arturo Prat University · CLPontificia Universidad Católica de Chile · CLUniversity of Talca · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reaction of 2-acetyl- and 2-benzoyl-1,4-naphthoquinone with (

Indexed as

Amino AcidsAntineoplastic AgentsCell Line, TumorCell SurvivalHumansMolecular StructureNaphthoquinonesStructure-Activity RelationshipVinyl CompoundsAmino AcidsAntineoplastic AgentsNaphthoquinonesVinyl Compounds2-acylnaphthoquinonescytotoxic activitiesenaminonesquinone amino acid conjugatesα-amino acid methyl esters

Identifiers

PMID29261169
PMCPMC6149812
OpenAlexW2778795476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.