Evidence map›Paper›PMID 29261141›Full record

ArticleInternational journal of molecular sciences2017

Evaluation of the Expression of Amine Oxidase Proteins in Breast Cancer.

Woo Young Sun, Junjeong Choi, Yoon Jin Cha, Ja Seung Koo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

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  16. Effects of neoadjuvant therapies on genetic regulation of targeted pathways in ER+ primary ductal breast carcinoma: A meta-analysis of microarray datasets.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Woo Young SunDepartment of Surgery, Daejeon St. Mary's Hospital, College of Medicine, The Cathololic University of Korea, Seoul 06591, Korea. sun2729@naver.com.ORCID 0000-0002-5447-4266
Junjeong ChoiCollege of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon 21988, Korea. junjeong@gmail.com.ORCID 0000-0003-1339-593X
Yoon Jin ChaDepartment of Pathology, Yonsei University College of Medicine, Seoul 03722, Korea. yooncha@yuhs.ac.
Ja Seung KooDepartment of Pathology, Yonsei University College of Medicine, Seoul 03722, Korea. kjs1976@yuhs.ac.ORCID 0000-0003-4546-4709
Yonsei University · KRThe Catholic University of Korea Daejeon St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to evaluate the expression of amine oxidase proteins in breast cancer and their clinical implications. We performed immunohistochemical staining of amine oxidase proteins (LOX, lysyl oxidase, AOC3, amine oxidase, MAOA, monoamine oxidase A, MAOB, monoamine oxidase B). Based on their hormone receptors, such as estrogen receptor (ER) and progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2), and Ki-67 immunohistochemical staining, breast cancer was divided into four molecular subtypes: luminal A, luminal B, HER-2 type, and triple-negative breast cancer (TNBC). Luminal A was observed in 380 cases (49.4%), luminal B in 224 (29.1%), HER-2 type in 68 (8.8%), and TNBC in 98 (12.7%). Stromal AOC3, MAO-A, and MAO-B expression varied according to molecular subtypes. Stromal AOC3 expression was high in luminal B and HER-2 type and MAO-A expression was high in luminal A and luminal B (

Indexed as

Biomarkers, TumorBreast NeoplasmsCarcinoma, DuctalErb-b2 Receptor Tyrosine KinasesFemaleHumansMiddle AgedMonoamine OxidaseProtein-Lysine 6-OxidaseReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesMonoamine OxidaseProtein-Lysine 6-OxidaseReceptors, EstrogenReceptors, Progesteroneamine oxidasebreast cancerestrogen receptorhuman epidermal growth factor receptor 2progesterone receptor

Identifiers

PMID29261141
PMCPMC5751373
OpenAlexW2776482217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.