Evidence map›Paper›PMID 29261131›Full record

ReviewBiomedicines2017

Histology of Non-Melanoma Skin Cancers: An Update.

Giovanni Paolino, Michele Donati, Dario Didona, Santo Raffaele Mercuri, Carmen Cantisani

Abstract readReview
In one paragraph

Review in Biomedicines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Small RNA sequencing of formalin-fixed paraffin embedded human skin biopsies reveals miRNA signatures for actinic keratosis and squamous cell carcinoma.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Advancing Cancer Research: Current Knowledge on Cutaneous Neoplasia.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giovanni PaolinoDermatology and Cosmetology, IRCCS San Raffaele Hospital, 20132 Milan, Italy. paolgio@libero.it.
Michele DonatiDepartment of Pathology, Università Campus Biomedico, 00161 Rome, Italy. micheledonati25@gmail.com.
Dario DidonaFirst Division of Dermatology, IRCCS Istituto Dermopatico dell'Immacolata, 00161 Rome, Italy. dario.didona@gmail.com.
Santo Raffaele MercuriDermatology and Cosmetology, IRCCS San Raffaele Hospital, 20132 Milan, Italy. mercuri.santoraffaele@hsr.it.
Carmen CantisaniDepartment of Dermatology, Dipartimento di Medicina Interna e Specialità Mediche, La Sapienza University of Rome, 00161 Rome, Italy. carmencantisanister@gmail.com.ORCID 0000-0003-2181-951X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-melanoma skin cancer (NMSC) is the most frequently diagnosed cancer in humans. Several different non-melanoma skin cancers have been reported in the literature, with several histologic variants that frequently cause important differential diagnoses with other cutaneous tumors basal cell carcinoma (BCC) is the most common malignant skin tumor, with different histologic variants that are associated with a greater or less aggressive behavior and that usually may be confused with other primitive skin tumors. Actinic keratosis, Bowen's disease, keratoacanthoma, and invasive squamous cell carcinoma (SCC) correspond to the other line of NMSC, that may have only local tumoral behavior, easy to treat and with local management (as in the case of actinic keratosis (AK), Bowen's disease, and keratoacanthoma) or a more aggressive behavior with a potential metastatic spread, as in case of invasive SCC. Therefore, histopathology serves as the gold standard during daily clinical practice, in order to improve the therapeutical approaches to patients with NMSC and to understand the distinct histopathological features of NMSC. Here, we reported the main pathological features of different non-melanoma skin cancers.

Indexed as

basal cell carcinomadiagnosisnon-melanoma skin cancerspathologysquamous cell carcinoma

Identifiers

PMID29261131
PMCPMC5744095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.