Evidence map›Paper›PMID 29261110›Full record

ArticleNutrients2017

Recent Development of Prebiotic Research-Statement from an Expert Workshop.

Giorgio La Fata, Robert A Rastall, Christophe Lacroix, Hermie J M Harmsen, M Hasan Mohajeri, Peter Weber, Robert E Steinert

Abstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Regulatory effect ofFrontiers in microbiology · 2024
    Review
  5. Review
  6. Review
  7. Physicochemical characteristics ofFood chemistry: X · 2022
    Article
  8. Article
  9. Frontiers in nutrition · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giorgio La FataDSM Nutritional Products Ltd., R & D Human Nutrition and Health, P.O. Box 2676, CH-4002 Basel, Switzerland. giorgio.lafata@dsm.com.
Robert A RastallDepartment of Food and Nutritional Science, The University of Reading, Whiteknights Campus, Reading RG6 6AP, UK. r.a.rastall@reading.ac.uk.
Christophe LacroixDepartment of Health Sciences and Technology, Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zurich, CH-8092 Zürich, Switzerland. christophe.lacroix@hest.ethz.ch.
Hermie J M HarmsenDepartment of Medical Microbiology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands. h.j.m.harmsen@umcg.nl.
M Hasan MohajeriDSM Nutritional Products Ltd., R & D Human Nutrition and Health, P.O. Box 2676, CH-4002 Basel, Switzerland. hasan.mohajeri@dsm.com.
Peter WeberDSM Nutritional Products Ltd., R & D Human Nutrition and Health, P.O. Box 2676, CH-4002 Basel, Switzerland. peter-weber@unity-mail.de.
Robert E SteinertDSM Nutritional Products Ltd., R & D Human Nutrition and Health, P.O. Box 2676, CH-4002 Basel, Switzerland. robert.steinert@dsm.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dietary prebiotic is defined as 'a substrate that is selectively utilized by host microorganisms conferring a health benefit'. Although this definition evolved concomitantly with the knowledge and technological developments that accrued in the last twenty years, what qualifies as prebiotic continues to be a matter of debate. In this statement, we report the outcome of a workshop where academic experts working in the field of prebiotic research met with scientists from industry. The workshop covered three main topics: (i) evolution of the prebiotic concept/definition; (ii) the gut modeling in vitro technology PolyFermS to study prebiotic effects; and (iii) the potential novel microbiome-modulating effects associated with vitamins. The future of prebiotic research is very promising. Indeed, the technological developments observed in recent years provide scientists with powerful tools to investigate the complex ecosystem of gut microbiota. Combining multiple in vitro approaches with in vivo studies is key to understanding the mechanisms of action of prebiotics consumption and their potential beneficial effects on the host.

Indexed as

Gastrointestinal MicrobiomePrebioticsAnimalsDietGastrointestinal TractHumansMicrobiotaNutritional Physiological PhenomenaResearchTerminology as TopicPrebioticsgut microbiotahealthy gutprebiotics and health benefits

Identifiers

PMID29261110
PMCPMC5748826

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.