Evidence map›Paper›PMID 29260893›Full record

ArticleThe British journal of radiology2018

Accuracy of coronary artery calcium scoring with tube current reduction by 75%, using an adaptive iterative reconstruction algorithm.

Reny Luhur, Joanne D Schuijf, Jürgen Mews, Jörg Blobel, Bernd Hamm, Alexander Lembcke

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Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Reny Luhur1 Department of Radiology, Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Berlin , Germany.
Joanne D Schuijf2 Center for Medical Research & Development Europe,Toshiba Medical Systems Europe BV , Toshiba Medical Systems Europe BV , Zoetermeer , Netherlands.
Jürgen Mews2 Center for Medical Research & Development Europe,Toshiba Medical Systems Europe BV , Toshiba Medical Systems Europe BV , Zoetermeer , Netherlands.
Jörg Blobel2 Center for Medical Research & Development Europe,Toshiba Medical Systems Europe BV , Toshiba Medical Systems Europe BV , Zoetermeer , Netherlands.
Bernd Hamm1 Department of Radiology, Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Berlin , Germany.
Alexander Lembcke1 Department of Radiology, Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Charité - Universitätsmedizin Berlin, Campus Charité Mitte , Berlin , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the accuracy of an iterative reconstruction (IR) technique for coronary artery calcium scoring with reduced radiation dose.

methods163 consecutive patients underwent twofold scanning by 320-row detector CT at 120 kVp. A low-dose scan at 25% tube current but with standard scan length (14 cm) was followed by a standard dose scan with routine tube current but reduced scan length (10 cm). Reduced dose images were constructed using filtered back-projection (FBP) and IR (adaptive iterative dose reduction in three dimensions). The standard dose scan reconstructed with FBP served as the gold standard for comparisons. Image noise and Agatston coronary calcium scores were determined and compared between the groups.

resultsCompared with FBP at standard dose, noise at reduced dose increased markedly with FBP but remained low with IR. Mean Agatston score with FBP at reduced dose showed a significant increase as compared with FBP at standard dose. No significant difference was observed when applying IR at reduced dose. At reduced dose, 38 (23.3%) patients were reassigned to a different cardiovascular risk category with FBP but only 8 (4.9%) with IR. Out of 47 patients with a zero Agatston score, 15 patients (31.9%) were false-positive with FBP at reduced dose, but no false positives were found with IR.

conclusionIR allows accurate coronary artery calcium scoring with a radiation dose reduced by 75%. Advances in knowledge: The application of adaptive iterative dose reduction in three dimensions allows the maintenance of accurate Agatston scores and risk stratification at significantly reduced tube current, thus reducing the patient's exposure to ionizing radiation.

Indexed as

AgedAlgorithmsCoronary DiseaseFemaleHumansMaleRadiation DosageRadiographic Image Interpretation, Computer-AssistedRisk AssessmentTomography, X-Ray ComputedVascular Calcification

Identifiers

PMID29260893
PMCPMC5966005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.