Evidence map›Paper›PMID 29260861›Full record

ArticleAnalytical chemistry2018

Whole-Cell Pseudomonas aeruginosa Localized Surface Plasmon Resonance Aptasensor.

Jiayun Hu, Kaiyu Fu, Paul W Bohn

Abstract read
In one paragraph

Article in Analytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. A Novel Methylene Blue Indicator-Based Aptasensor for Rapid Detection ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Aptamer-based approaches for the detection of waterborne pathogens.International microbiology : the official journal of the Spanish Society for Microbiology · 2021
    Review
  13. Whole Cell Recognition ofBiosensors · 2021
    Article
  14. Article
  15. Review
  16. Microbial biosensors for recreational and source waters.Journal of microbiological methods · 2020
    Review
  17. Review
  18. Article
  19. A Fluorescent Sensor Based on Reversible Addition-Fragmentation Chain Transfer Polymerization for the Early Diagnosis of Non-small Cell Lung Cancer.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiayun HuDepartment of Chemistry and Biochemistry, University of Notre Dame , Notre Dame, Indiana 46556, United States.ORCID 0000-0001-9749-5924
Kaiyu FuDepartment of Chemistry and Biochemistry, University of Notre Dame , Notre Dame, Indiana 46556, United States.ORCID 0000-0002-7899-0388
Paul W BohnDepartment of Chemistry and Biochemistry, University of Notre Dame , Notre Dame, Indiana 46556, United States.ORCID 0000-0001-9052-0349
University of Notre Dame · US

Funding

Characterization of Biofilms by Correlated Mass Spectrometric and Raman ImagingR01AI113219 · NIAID · UNIVERSITY OF NOTRE DAME · PI SHROUT, JOSHUA · 2014 to 2023
$4.7M
NIAID NIH HHS R01 AI113219
6 · The paper itself

Abstract

The detection of whole-cell Pseudomonas aeruginosa presents an intriguing challenge with direct applications in health care and the prevention of nosocomial infection. To address this problem, a localized surface plasmon resonance (LSPR) based sensing platform was developed to detect whole-cell Pseudomonas aeruginosa strain PAO1 using a surface-confined aptamer as an affinity reagent. Nanosphere lithography (NSL) was used to fabricate a sensor surface containing a hexagonal array of Au nanotriangles. The sensor surface was subsequently modified with biotinylated polyethylene glycol (Bt-PEG) thiol/PEG thiol (1:3), neutravidin, and biotinylated aptamer in a sandwich format. The 1:3 (v/v) ratio of Bt-PEG thiol/PEG thiol was specifically chosen to maximize PAO1 binding while minimizing nonspecific adsorption and steric hindrance. In contrast to prior whole-cell LSPR work, the LSPR wavelength shift was shown to be linearly related to bacterial concentration over the range of 10-10

Indexed as

Aptamers, NucleotideAvidinBase SequenceBiosensing TechniquesBiotinGoldLimit of DetectionNanostructuresPseudomonas aeruginosaSurface Plasmon ResonanceAptamers, NucleotideAvidinBiotinGoldneutravidin

Identifiers

PMID29260861
PMCPMC5907805
OpenAlexW2778491259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.