Evidence map›Paper›PMID 29260455›Full record

ArticleJournal of the American Society for Mass Spectrometry2018

Iodine-Containing Mass-Defect-Tuned Dendrimers for Use as Internal Mass Spectrometry Calibrants.

Joseph A Giesen, Benjamin J Diament, Scott M Grayson

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. SpheriCalRapid communications in mass spectrometry : RCM · 2021
    Article
  4. Article
  5. Mass spectrometry of dendrimers.Mass spectrometry reviews
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joseph A GiesenDepartment of Chemistry, 2015 Stern Hall, Tulane University, New Orleans, LA, 70118-5636, USA.
Benjamin J DiamentDepartment of Computer Science and Engineering, University of Washington, Box 352350, Seattle, WA, 98195-2350, USA.
Scott M GraysonDepartment of Chemistry, 2015 Stern Hall, Tulane University, New Orleans, LA, 70118-5636, USA. sgrayson@tulane.edu.
Tulane University · USUniversity of Washington · US

Funding

American Chemical Society Petroleum Research Fund 53890-ND-7
6 · The paper itself

Abstract

Calibrants based on synthetic dendrimers have been recently proposed as a versatile alternative to peptides and proteins for both MALDI and ESI mass spectrometry calibration. Because of their modular synthetic platform, dendrimer calibrants are particularly amenable to tailoring for specific applications. Utilizing this versatility, a set of dendrimers has been designed as an internal calibrant with a tailored mass defect to differentiate them from the majority of natural peptide analytes. This was achieved by incorporating a tris-iodinated aromatic core as an initiator for the dendrimer synthesis, thereby affording multiple calibration points (m/z range 600-2300) with an optimized mass-defect offset relative to all peptides composed of the 20 most common proteinogenic amino acids. Graphical abstract ᅟ.

Indexed as

CalibrantDendrimerESI MSMALDI-TOF MSMass defectPeptides

Identifiers

PMID29260455
OpenAlexW2777237560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.