ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018
Comorbidity amplifies the effects of post-9/11 posttraumatic stress disorder trajectories on health-related quality of life.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Posttraumatic Stress Disorder Symptoms in World Trade Center Responders: A Feasibility and Acceptability Study.International journal of environmental research and public health · 2026Trial
- Exposure to the World Trade Center Disaster, Health, and Health-Related Quality of Life Nearly 20 Years After 9/11.American journal of industrial medicine · 2025Article
- Supporting young people through the COVID-19 pandemic and beyond: a multi-site qualitative longitudinal study.BMC health services research · 2024Article
- A history of PTSD changes the way people express themselves during the COVID-19 pandemic.European journal of psychotraumatology · 2024Article
- Prevalence and risk factors of PTSD symptoms: a 3-month follow-up study.Therapeutic advances in psychopharmacology · 2024Article
- Mortality after the 9/11 terrorist attacks among world trade center health registry enrollees with cancer.Cancer medicine · 2023Article
- Posttraumatic Stress Disorder Mediates the Association between Traumatic World Trade Center Dust Cloud Exposure and Ongoing Systemic Inflammation in Community Members.International journal of environmental research and public health · 2022Article
- Adaptation of the barriers to help-seeking for trauma (BHS-TR) scale: a cross-cultural cognitive interview study with female intimate partner violence survivors in Iceland.Journal of patient-reported outcomes · 2021Article
- PTSD and Depression in Healthcare Workers in the Italian Epicenter of the COVID-19 Outbreak.Clinical practice and epidemiology in mental health : CP & EMH · 2021Article
- Association Between Posttraumatic Stress Disorder and Mortality Among Responders and Civilians Following the September 11, 2001, Disaster.JAMA network open · 2020Article
- The Burden of Subthreshold Posttraumatic Stress Disorder in World Trade Center Responders in the Second Decade After 9/11.The Journal of clinical psychiatry · 2020Article
- Longitudinal Change of PTSD Symptoms in Community Members after the World Trade Center Destruction.International journal of environmental research and public health · 2019Article
- Pulmonary Fibrosis among World Trade Center Responders: Results from the WTC Health Registry Cohort.International journal of environmental research and public health · 2019Article
- Persistent mental and physical health impact of exposure to the September 11, 2001 World Trade Center terrorist attacks.Environmental health : a global access science source · 2019Article
- Re-experiencing 9/11-Related PTSD Symptoms Following Exposure to Hurricane Sandy.International journal of emergency mental health · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeThe present study aims to examine the impact of physical and mental health comorbidities on the association between post-9/11 posttraumatic stress disorder (PTSD) trajectories over 10 years and health-related quality of life (HRQOL) among 9/11-exposed persons.
methods30,002 responding adult World Trade Center Health Registry enrollees reporting no pre-9/11 PTSD were studied. PTSD trajectories (chronic, delayed, remitted, no PTSD) were defined based on a 17-item PTSD Checklist-Specific to 9/11 across three waves of survey data. Three indicators of poor HRQOL were defined based on CDC HRQOL-4 measures. We computed age-adjusted prevalence of physical and mental health comorbidity (depression/anxiety) by PTSD trajectory and used modified Poisson regression to assess the effect of PTSD trajectory on poor HRQOL prevalence, accounting for comorbidity.
resultsAge-adjusted prevalence of overall comorbid conditions was 95.8 and 61.4% among the chronic and no-PTSD groups, respectively. Associations between 9/11-related PTSD trajectories and poor HRQOL were significant and became greater when comorbidity was included. Adjusted prevalence ratios were elevated for fair/poor health status (APR 7.3, 95% CI 6.5, 8.2), ≥ 14 unhealthy days (4.7; 95% CI 4.4, 5.1), and ≥ 14 activity limitation days during the last 30 days (9.6; 95% CI 8.1, 11.4) in the chronic PTSD group with physical and mental health comorbidity compared to those without PTSD and comorbidity; similar associations were observed for delayed PTSD.
conclusionsTen years post-9/11 physical and mental health comorbidities have a substantial impact on the PTSD trajectories and HRQOL association. The need for early identification and treatment of PTSD and comorbidity should be emphasized to potentially improve HRQOL.
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