Evidence map›Paper›PMID 29260412›Full record

ArticleJournal of natural medicines2018

Inner morphological and chemical differentiation of Boehmeria species.

Kazi-Marjahan Akter, Hye-Jin Kim, Atif Ali Khan Khalil, Woo Sung Park, Mi Kyeong Lee, Jong Hee Park, Mi-Jeong Ahn

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Article in Journal of natural medicines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kazi-Marjahan AkterCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Korea.
Hye-Jin KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Korea.
Atif Ali Khan KhalilCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Korea.
Woo Sung ParkCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Korea.
Mi Kyeong LeeCollege of Pharmacy, Chungbuk National University, Cheongju, 28644, Korea.
Jong Hee ParkCollege of Pharmacy, Pusan National University, Busan, 46241, Korea.
Mi-Jeong AhnCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Korea. amj5812@gnu.ac.kr.

Funding

the National Research Foundation of Korea, the Ministry of Science, ICT & Future Planning 2017R1A2B4008859)the National Research Foundation of Korea, the Ministry of Science, ICT & Future Planning (NRF-2014R1A1A305070the Next-Generation BioGreen 21 Program, Rural Development Administration, Republic of Korea grant# No. PJ01106402)the Next-Generation BioGreen 21 Program, Rural Development Administration, Republic of Korea (SSAC
6 · The paper itself

Abstract

The present study was designed to establish quality control parameters for pharmacognostic evaluation and differentiation of eight locally derived Boehmeria species, B. gracilis, B. nivea, B. pannosa, B. platanifolia, B. quelpaertensis, B. spicata, B. splitgerbera, B. tricuspis, and two varieties named B. japonica var. longispica, B. nivea var. concolor, which have been utilized as the folk medicine, 'Mo-Si-Pool' in Korea. Although the outer morphological study of these species had been reported, there is no pharmacognostical description yet. Therefore, inner morphological evaluation on leaf midrib, petiole and stem of eight Boehmeria species and two varieties was accomplished along with preliminary phytochemical analysis by HPLC-DAD profiling. The microscopic data showed discriminative inner morphological characteristics such as collenchyma cell layer, thickness of cortex and xylem, frequency of druse and hairs, and number of vascular bundles. The HPLC profiles exhibited more than four characteristic peaks. The molecular ions of the four peaks (1-4) were tentatively identified by ESI-MS, and their structures were identified by NMR spectroscopy to be the flavonoids, rutin (1), isoquercetin (2) and kaempferol-3-O-rutinoside (3), and a phenanthroquinolizidine alkaloid, (-)-cryptopleurine (4). While compounds 1 and 2 were detected in all samples, compound 4 was determined only in B. japonica var. longispica, B. pannosa and B. quelpaertensis and B. splitgerbera. These findings provide the initial scientific criteria for proper identification and establishment of standards for use of Boehmeria species in traditional medicine.

Indexed as

BoehmeriaChromatography, High Pressure LiquidPhytochemicalsPlant ExtractsPhytochemicalsPlant ExtractsAlkaloidBoehmeria speciesHPLC profilesInner morphological characteristics

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.