Evidence map›Paper›PMID 29260366›Full record

ArticleEuropean radiology2018

Feasibility of free-breathing dynamic contrast-enhanced MRI of gastric cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with the conventional contrast-enhanced breath-hold 3D VIBE sequence.

Huan-Huan Li, Hui Zhu, Lei Yue, Yi Fu, Robert Grimm, Alto Stemmer, Cai-Xia Fu, Wei-Jun Peng

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  17. The role of MRI in the diagnosis and treatment of gastric cancer.Diagnostic and interventional radiology (Ankara, Turkey) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huan-Huan LiDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Hui ZhuDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Lei YueDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Yi FuDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Robert GrimmMR Applications Development, Siemens Healthcare, Erlangen, Germany.
Alto StemmerMR Applications Development, Siemens Healthcare, Erlangen, Germany.
Cai-Xia FuMR Applications Development, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China.
Wei-Jun PengDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China. cjr.pengweijun@vip.163.com.

Funding

the innovation funds for development of science and technology in PuDong new area PKJ2013-Y07
6 · The paper itself

Abstract

objectivesTo investigate the feasibility and diagnostic value of free-breathing, radial, stack-of-stars three-dimensional (3D) gradient echo (GRE) sequence ("golden angle") on dynamic contrast-enhanced (DCE) MRI of gastric cancer.

methodsForty-three gastric cancer patients were divided into cooperative and uncooperative groups. Respiratory fluctuation was observed using an abdominal respiratory gating sensor. Those who breath-held for more than 15 s were placed in the cooperative group and the remainder in the uncooperative group. The 3-T MRI scanning protocol included 3D GRE and conventional breath-hold VIBE (volume-interpolated breath-hold examination) sequences, comparing images quantitatively and qualitatively. DCE-MRI parameters from VIBE images of normal gastric wall and malignant lesions were compared.

resultsFor uncooperative patients, 3D GRE scored higher qualitatively, and had higher SNRs (signal-to-noise ratios) and CNRs (contrast-to-noise ratios) than conventional VIBE quantitatively. Though 3D GRE images scored lower in qualitative parameters compared with conventional VIBE for cooperative patients, it provided images with fewer artefacts. DCE parameters differed significantly between normal gastric wall and lesions, with higher Ve (extracellular volume) and lower Kep (reflux constant) in gastric cancer.

conclusionsThe free-breathing, golden-angle, radial stack-of-stars 3D GRE technique is feasible for DCE-MRI of gastric cancer. Dynamic enhanced images can be used for quantitative analysis of this malignancy. KEY POINTS: • Golden-angle radial stack-of-stars VIBE aids gastric cancer MRI diagnosis. • The 3D GRE technique is suitable for patients unable to suspend respiration. • Method scored higher in the qualitative evaluation for uncooperative patients. • The technique produced images with fewer artefacts than conventional VIBE sequence. • Dynamic enhanced images can be used for quantitative analysis of gastric cancer.

Indexed as

ArtifactsBreath HoldingAdultAgedContrast MediaEndoscopy, GastrointestinalFeasibility StudiesFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyReproducibility of ResultsStomach NeoplasmsContrast MediaDCEGolden-angle radial VIBEMagnetic resonance imagingStack of starsStomach neoplasms

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.