Evidence map›Paper›PMID 29260347›Full record

ArticleInflammation2018

Apolipoprotein M Protects Against Lipopolysaccharide-Induced Acute Lung Injury via Sphingosine-1-Phosphate Signaling.

Bin Zhu, Guang-Hua Luo, Yue-Hua Feng, Miao-Mei Yu, Jun Zhang, Jiang Wei, Chun Yang, Ning Xu, Xiao-Ying Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  3. Article
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  5. Article
  6. Article
  7. Article
  8. [Research advances of the roles of sphingosine-1-phosphate in acute lung injury].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Review
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Bin ZhuDepartment of Critical Care Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Guang-Hua LuoComprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Yue-Hua FengComprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Miao-Mei YuComprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Jun ZhangComprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Jiang WeiComprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213003, China.
Chun YangDepartment of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430030, China.
Ning XuDivision of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, 221 85, Lund, Sweden.
Xiao-Ying ZhangDepartment of Cardiothoracic Surgery, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, Jiangsu Province, 213003, China. zhangxy6689996@163.com.
Soochow University · CNLund University · SETongji Hospital · CN

Funding

"333 Project" of JiangSu Province BRA2016122Major Science and Technology Project of Changzhou Municipal Commission of Health and Family Planning ZD201505National Natural Science Foundation of China 81370372the Program of Bureau of Science and Technology Foundation of Changzhou CJ20159022
6 · The paper itself

Abstract

It had been demonstrated that apolipoprotein M (apoM) is an important carrier of sphingosine-1-phosphate (S1P) in blood, and the S1P has critical roles in the pathogenesis of sepsis-induced acute lung injury (ALI). In the present study, we investigated whether apoM has beneficial effects in a mouse model after lipopolysaccharide (LPS)-induced ALI. Forty-eight mice were divided into two groups: male C57BL/6 wild-type (apoM

Indexed as

Acute Lung InjuryAnilidesAnimalsApolipoproteins MBiomarkersInflammationLipopolysaccharidesLysophospholipidsMaleMiceOrganophosphonatesProtective AgentsReceptors, LysosphingolipidSignal TransductionSphingosine3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acidAnilidesApolipoproteins MBiomarkersLipopolysaccharidesLysophospholipidsOrganophosphonatesProtective AgentsReceptors, LysosphingolipidSphingosinesphingosine 1-phosphateacute lung injuryapolipoprotein Mlipopolysaccharidesphingosine-1-phosphatesphingosine-1-phosphate receptor 1

Identifiers

PMID29260347
OpenAlexW2778084379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.