Evidence map›Paper›PMID 29260115›Full record

ArticleAmerican journal of ophthalmology case reports2017

Changes in choroidal blood flow and choroidal thickness after treatment in two cases of pediatric anisohypermetropic amblyopia.

Ryuya Hashimoto, Juri Kawamura, Asato Hirota, Mizuho Oyamada, Asao Sakai, Takatoshi Maeno

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Early macular choroidal hemodynamic changes after faricimab loading in treatment-naïve diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  10. Acupuncture for pediatric bilateral amblyopia.Integrative medicine research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryuya HashimotoDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Juri KawamuraDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Asato HirotaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Mizuho OyamadaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Asao SakaiDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Takatoshi MaenoDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan.
Toho University · JPToho University Medical Center Sakura Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to examine the changes in choroidal blood flow (CBF) and central choroidal thickness (CCT) in children with anisohypermetropic amblyopia using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT). OBSERVATIONS: The patients were both 6-year-old Japanese male children with complaints of worsening right visual acuity and were diagnosed with anisohypermetropic amblyopia. The decimal best-corrected visual acuities (BCVAs) in cases 1 and 2 were both 0.5. In both cases, LSFG results demonstrated CBF impairment in amblyopic eyes compared with fellow eyes. EDI-OCT results also showed that the CCTs of amblyopic eyes were greater than those of fellow eyes at the initial visit. Several months after the first visit, the decimal BCVAs in both cases had improved to 1.0 because of treatment. Further, the CBF gradually increased along with a decrease in the CCT of the amblyopic eye. The axial lengths and spherical powers of the amblyopic eyes in the two cases were not different during follow-up. CONCLUSIONS AND IMPORTANCE: We have determined the changes in CBF and CCT in two children with anisohypermetropic amblyopia for the first time. CBF impairments may be involved in the pathogenesis of anisohypermetropic amblyopia, and LSFG may be useful in examining CBF in pediatric anisohypermetropic amblyopia.

Indexed as

Anisohypermetropic amblyopiaChildrenChoroidal blood flowChoroidal thicknessLaser speckle flowgraphy

Identifiers

PMID29260115
PMCPMC5731713
OpenAlexW2764276142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.