Evidence map›Paper›PMID 29259993›Full record

ArticleBioMed research international2017

A Study on Cytotoxic and Apoptotic Potential of a Triterpenoid Saponin (3-O-

Sameera R Samarakoon, Meran K Ediriweera, Chukwumaobim Daniel Uzochukwuwulu Nwokwu, Chamara Janaka Bandara, Kamani H Tennekoon, Poorna Piyathilaka, D Nedra Karunaratne, Veranja Karunaratne

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Anti-Tumor Potential ofAntioxidants (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Novel SynthesizedInternational journal of molecular sciences · 2021
    Article
  5. Article
  6. Methylenetetrahydrofolate Dehydrogenase 1 Silencing Expedites the Apoptosis of Non-Small Cell Lung Cancer Cells via Modulating DNA Methylation.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sameera R SamarakoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, 03 Colombo, Sri Lanka.ORCID 0000-0002-5278-4770
Meran K EdiriweeraInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, 03 Colombo, Sri Lanka.ORCID 0000-0001-9393-9516
Chukwumaobim Daniel Uzochukwuwulu NwokwuInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, 03 Colombo, Sri Lanka.
Chamara Janaka BandaraInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, 03 Colombo, Sri Lanka.
Kamani H TennekoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, 03 Colombo, Sri Lanka.ORCID 0000-0003-0608-4340
Poorna PiyathilakaDepartment of Biotechnology, Faculty of Agriculture and Plantation Management, Wayamba University of Sri Lanka, Makadura, Gonawila, Sri Lanka.
D Nedra KarunaratneDepartment of Chemistry, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka.
Veranja KarunaratneDepartment of Chemistry, Faculty of Science, University of Peradeniya, Peradeniya, Sri Lanka.ORCID 0000-0002-0092-3361
University of Colombo · LKUniversity of Peradeniya · LKWayamba University of Sri Lanka · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the major cause of cancer death among men. A number of natural compounds have proven to be useful in the treatmet of lung cancer. This study was aimed to determine cytotoxic and apoptotoic effects of a natural compound 3-O-

Indexed as

ApoptosisCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationDilleniaceaeGene Expression Regulation, NeoplasticHumansNeoplasm ProteinsOleanolic AcidOxidative StressSaponinsSignal TransductionTriterpenesNeoplasm ProteinsOleanolic AcidSaponinsTriterpenes

Identifiers

PMID29259993
PMCPMC5702947
OpenAlexW2767669651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.