Evidence map›Paper›PMID 29259908›Full record

ArticleInternational journal of ophthalmology2017

Optic nerve compression: the role of the lamina cribrosa and translaminar pressure.

Mario R Romano, Gilda Cennamo, Maria Angelica Breve, Michela Piedepalumbo, Claudio Iovino, Nunzio Velotti, Giovanni Cennamo

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mario R RomanoDepartment of Biomedical Sciences, Humanitas University, Milan 20089, Italy.
Gilda CennamoDepartment of Public Health, University of Naples Federico II, Naples 80131, Italy.
Maria Angelica BreveDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples 80100, Italy.
Michela PiedepalumboDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples 80100, Italy.
Claudio IovinoDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples 80100, Italy.
Nunzio VelottiDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples 80100, Italy.
Giovanni CennamoDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples 80100, Italy.
University of Naples Federico II · ITHumanitas University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe the morphological changes of the lamina cribrosa (LC) in patients with optic nerve compression.

methodsCross-sectional study. Twenty eyes with optic nerve compression, affected by Graves' ophthalmopathy (GO) were compared with 18 refractive error-matched healthy eyes. The following examinations were performed: best-corrected visual acuity (BCVA), intraocular pressure, optic nerve echography, visual field, SD-OCT including the retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and LC thickness and extent.

resultsA-scan revealed significant differences in the subarachnoid space (SAS) between the affected and control groups. LC thickness and LC area were 233 µm (SD 23) and 0.41 mm

conclusionOptic nerve compression reduces the SAS thereby altering the morphology of LC thickness and causing GCC damage.

Indexed as

lamina cribrosaoptic nerve compressiontranslaminar pressure

Identifiers

PMID29259908
PMCPMC5733517
OpenAlexW2790567625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.