ArticleInternational journal of endocrinology2017
Mediastinal Lymph Node Metastases in Thyroid Cancer: Characteristics, Predictive Factors, and Prognosis.
Article in International journal of endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The 2024 revised clinical guidelines on the management of thyroid tumors by the Japan Association of Endocrine Surgery.Endocrine journal · 2025Guideline
- Clinical significance of level VII lymph node metastasis in papillary thyroid cancer.Scientific reports · 2025Article
- Unmasking Hidden Mediastinal Involvement in Papillary Thyroid Carcinoma: A Case Report on the Diagnostic Utilization of EBUS-TBNA.Case reports in pulmonology · 2025Article
- Anterior Mediastinal Lymph Node Metastasis of Intrahepatic Cholangiocarcinoma: A Case Report and Literature Review.Surgical case reports · 2025Article
- Skip and Mediastinal Metastasis in Papillary Thyroid Cancer.Radiology. Imaging cancer · 2023Article
- Clinical outcomes of combined cervical and transthoracic surgical approaches in patients with advanced thyroid cancer.Head & neck · 2023Article
- Video-assisted superior mediastinal lymphadenectomy for papillary thyroid cancer: a case report.Annals of the Royal College of Surgeons of England · 2022Article
- Thoracoscopy-assisted treatment for mediastinal metastasis of thyroid cancer: a case report.The Journal of international medical research · 2022Article
- Mediastinal Lymph Node Metastasis from Head and Neck Cancer: Predictive Factors and Imaging Features.Taehan Yongsang Uihakhoe chi · 2021Article
- Video mediastinoscopy-assisted superior mediastinal dissection in the treatment of thyroid carcinoma with mediastinal lymphadenopathy: preliminary results.BMC surgery · 2021Article
- Usefulness of PET/CT withDiagnostics (Basel, Switzerland) · 2021Article
- The association between tumor's location and cervical lymph nodes metastasis in papillary thyroid cancer.Gland surgery · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMediastinal lymph node metastases (MLNM) have not been extensively studied. The aim of this study is to investigate the characteristics, predictive factors, and prognosis of MLNM in thyroid cancer.
methodsThis is a retrospective study based on the thyroid cancer patients with MLNM at our institution from 2008 to 2015.
resultsIn total, 73 thyroid cancer patients with positive MLNM were included in this study. It contained sixty patients (82.2%) with papillary thyroid carcinoma (PTC), twelve (16.4%) with medullary thyroid carcinoma, and one (1.4%) with anaplastic thyroid carcinoma. Forty-eight patients had the surgery as initial treatment. Fifty-three (72.6%) patients remained disease-free, and fifteen (20.5%) developed a regional recurrence. Distant metastases occurred in four (5.5%) patients and five (6.8%) patients died. Five-year overall survival rate and disease-free survival (DFS) rate of the PTC patients for initial treatment are 95.4% and 77.2%, respectively. Extrathyroidal extension and multiple lymph nodes involved were associated with DFS in PTC patients.
conclusionsInitial therapeutic control is very important for the thyroid cancer patients. Extrathyroidal extension and multiple mediastinal lymph nodes involved were the influence factors of prognosis in the thyroid cancer patients with MLNM.
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