Evidence map›Paper›PMID 29259583›Full record

ArticleFrontiers in microbiology2017

Inhibition of Tissue Matrix Metalloproteinases Interferes with

Venkata R Parasa, Jagadeeswara R Muvva, Jeronimo F Rose, Clara Braian, Susanna Brighenti, Maria Lerm

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 51 citations in OpenAlex.

  1. Doxycycline host-directed therapy in human pulmonary tuberculosis.The Journal of clinical investigation · 2021
    Trial
  2. Review
  3. Towards host-directed therapy: The role of matrix metalloproteinases in the immunopathogenesis of tuberculosis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Review
  4. Review
  5. Review
  6. Host-directed therapy for tuberculosis.European journal of medical research · 2025
    Review
  7. Article
  8. Model systems to studyFrontiers in cellular and infection microbiology · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Inflammatory Pathways in Sarcoidosis.Advances in experimental medicine and biology · 2021
    Article
  20. Innate Immune Responses ofFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Venkata R ParasaDivision of Medical Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Jagadeeswara R MuvvaCenter for Infectious Medicine, Karolinska Institute, Stockholm, Sweden.
Jeronimo F RoseDivision of Medical Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Clara BraianDivision of Medical Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Susanna BrighentiCenter for Infectious Medicine, Karolinska Institute, Stockholm, Sweden.
Maria LermDivision of Medical Microbiology and Molecular Medicine, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Linköping University · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulomas are hallmarks of pulmonary tuberculosis (TB) and traditionally viewed as host-protective structures. However, recent evidence suggest that

Indexed as

granulomamatrix metalloproteinasestissue inhibitor of matrix metalloproteinasestissue modelstuberculosis

Identifiers

PMID29259583
PMCPMC5723394
OpenAlexW2773946736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.