Evidence map›Paper›PMID 29259557›Full record

ArticleFrontiers in physiology2017

Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca

Jens G Danielczok, Emmanuel Terriac, Laura Hertz, Polina Petkova-Kirova, Franziska Lautenschläger, Matthias W Laschke, Lars Kaestner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 116 citations in OpenAlex.

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  11. The uremic solute 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) may enhance eryptosis and increase erythrocyte osmotic fragility through potential activation of PIEZO1.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  12. Article
  13. Shape-Dependent Structural Order of Red Blood Cells.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  14. Review
  15. Lysis of human erythrocytes due to Piezo1-dependent cytosolic calcium overload as a mechanism of circulatory removal.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Piezo1, the new actor in cell volume regulation.Pflugers Archiv : European journal of physiology · 2024
    Review
  17. Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jens G DanielczokInstitute for Molecular Cell Biology, Saarland University, Homburg, Germany.
Emmanuel TerriacExperimental Physics, Saarland University, Saarbrücken, Germany.
Laura HertzInstitute for Molecular Cell Biology, Saarland University, Homburg, Germany.
Polina Petkova-KirovaInstitute for Molecular Cell Biology, Saarland University, Homburg, Germany.
Franziska LautenschlägerExperimental Physics, Saarland University, Saarbrücken, Germany.
Matthias W LaschkeInstitute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany.
Lars KaestnerExperimental Physics, Saarland University, Saarbrücken, Germany.
Saarland University · DELeibniz-Institute for New Materials · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When red blood cells (RBCs) pass constrictions or small capillaries they need to pass apertures falling well below their own cross section size. We used different means of mechanical stimulations (hypoosmotic swelling, local mechanical stimulation, passing through microfluidic constrictions) to observe cellular responses of human RBCs in terms of intracellular Ca

Indexed as

Ca2+ imagingdorsal skinfold chamberhSK4 (KCNN4)microfluidicsPiezo1RBC deformation

Identifiers

PMID29259557
PMCPMC5723316
OpenAlexW2774623822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.