ArticleReproductive medicine and biology2017
Leydig cell tumor of the testis, presenting with azoospermia.
Article in Reproductive medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Transcriptomic Profiling of Canine Testicular Leydig Cell Tumors Uncovers Key Upregulated Gene Pathways.Animals : an open access journal from MDPI · 2026Article
- Case - Leydig cell hyperplasia A rare ipsilateral co-occurrence with seminoma highlighting the value of 17-OHP in the evaluation of male infertility.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Article
- Interstitial Leydig Cell Tumorigenesis-Leptin and Adiponectin Signaling in Relation to Aromatase Expression in the Human Testis.International journal of molecular sciences · 2020Article
- Leydig cell tumor of the testis, presenting with azoospermia.Reproductive medicine and biology · 2017Article
- COEXISTENCE OF LEYDIG CELL TUMOUR AND SERTOLI CELL-ONLY SYNDROME WITH AN INCOMPATIBLE HORMONE PROFILE AND AZOOSPERMIA.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case: A case of Leydig cell tumor, associated with azoospermia, is presented. Outcome: The levels of sex hormones obviously were decreased, including luteinizing hormone (LH) and follicle-stimulating hormone (FSH), with elevated testosterone. Computed tomography revealed no adrenal gland tumor, but a significant calcification in the right scrotal content was observed. He received a right radical orchiectomy and then he was unable to ejaculate. An endocrine panel revealed significantly decreased levels of testosterone and the low LH level had remained. Hormone replacement therapy with combined LH and FSH successfully recovered and preserved spermatogenesis. Conclusions: Although the patient's sexual function deteriorated after surgery, hormone replacement therapy was successful in establishing spermatogenesis.
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Registered trials
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