Evidence map›Paper›PMID 29259488›Full record

ArticleReproductive medicine and biology2017

Evaluation of transfer media containing different concentrations of hyaluronan for human in vitro fertilization.

Takuji Nishihara, Yoshiharu Morimoto

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Takuji NishiharaDivision of Culture Environment HORAC Grand Front Osaka Clinic Osaka Japan.ORCID 0000-0001-7841-5503
Yoshiharu MorimotoDivision of Culture Environment HORAC Grand Front Osaka Clinic Osaka Japan.
Osaka Nishi Clinic · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of the present prospective study was to investigate the efficacy of hyaluronan (HA) using two different concentrations as embryo transfer media for in vitro fertilization embryo transfer cycles. Methods: A total of 169 cycles undergoing fresh embryo transfer on day 2 or 3, 561 cycles undergoing frozen-thawed embryo transfer on day 2 or 3, and 484 cycles of frozen-thawed blastocyst transfer were included in this study. Patients were randomly divided into two groups: transferred with low (l-HA) or high (h-HA) concentrations of HA in transfer media. Results: In the case of fresh embryo transfer cycles, no significant differences were observed in the pregnancy (l-HA 27.2%, h-HA 31.2%), implantation (l-HA 22.1%, h-HA 24.2%), or abortion (l-HA 24.0%, h-HA 20.8%) rates between the two groups. In the case of frozen-thawed embryo transfer cycles, no significant differences were noted in the pregnancy (l-HA 20.9%, h-HA 22.9%), implantation (l-HA 13.4%, h-HA 15.8%), or abortion (l-HA 17.2%, h-HA 21.5%) rates. In the case of frozen-thawed blastocyst transfer cycles, no significant differences were observed in the pregnancy (l-HA 46.0%, h-HA 41.8%), implantation (l-HA 45.8%, h-HA 41.3%), or abortion (l-HA 17.6%, h-HA 26.9%) rates. Conclusion: The present results showed that pregnancy, implantation, and abortion rates with transfer media containing different HA concentrations were similar.

Indexed as

hyaluronanhyaluronic acidin vitro fertilization and embryo transfertransfer medium

Identifiers

PMID29259488
PMCPMC5715902
OpenAlexW2747105057

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.