Evidence map›Paper›PMID 29259455›Full record

ReviewReproductive medicine and biology2017

Human male infertility and its genetic causes.

Toshinobu Miyamoto, Gaku Minase, Takeshi Shin, Hiroto Ueda, Hiroshi Okada, Kazuo Sengoku

Open access · goldAbstract readReview
In one paragraph

Review in Reproductive medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Is sperm telomere length altered in teratozoospermia specimens? A case-control study.International journal of reproductive biomedicine · 2023
    Article
  9. Article
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  11. Article
  12. Microenvironment for spermatogenesis and sperm maturation.Histochemistry and cell biology · 2022
    Review
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  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Toshinobu MiyamotoDepartment of Obstetrics and Gynecology Asahikawa Medical University Asahikawa Japan.
Gaku MinaseDepartment of Obstetrics and Gynecology Asahikawa Medical University Asahikawa Japan.
Takeshi ShinDepartment of Urology Dokkyo Medical University Koshigaya Hospital Koshigaya City Japan.
Hiroto UedaDepartment of Obstetrics and Gynecology Asahikawa Medical University Asahikawa Japan.
Hiroshi OkadaDepartment of Urology Dokkyo Medical University Koshigaya Hospital Koshigaya City Japan.
Kazuo SengokuDepartment of Obstetrics and Gynecology Asahikawa Medical University Asahikawa Japan.
Asahikawa Medical University · JPDokkyo Medical University Saitama Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infertility affects about 15% of couples who wish to have children and half of these cases are associated with male factors. Genetic causes of azoospermia include chromosomal abnormalities, Y chromosome microdeletions, and specific mutations/deletions of several Y chromosome genes. Many researchers have analyzed genes in the AZF region on the Y chromosome; however, in 2003 the Methods: We mainly describe the Results: Up to now, The 17 genes causing male infertility by their mutation have been reported in human. Conclusions: Infertility caused by nonobstructive azoospermia (NOA) is very important in the field of assisted reproductive technology. Even with the aid of chromosomal analysis, ultrasonography of the testis, and detailed endocrinology, only MD-TESE can confirm the presence of immature spermatozoa in the testes. We strongly hope that these studies help clinics avoid ineffective MD-TESE procedures.

Indexed as

azoospermiamale infertilitymutationPLK4SYCP3

Identifiers

PMID29259455
PMCPMC5661822
OpenAlexW2598045563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.