Evidence map›Paper›PMID 29259417›Full record

ReviewReproductive medicine and biology2016

Conceptus implantation and placentation: molecules related to epithelial-mesenchymal transition, lymphocyte homing, endogenous retroviruses, and exosomes.

Kazuhiko Imakawa, Rulan Bai, Hiroshi Fujiwara, Kazuya Kusama

Abstract readReview
In one paragraph

Review in Reproductive medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kazuhiko ImakawaLaboratory of Theriogenology and Animal Breeding, Graduate School of Agricultural and Life SciencesThe University of Tokyo1-1-1 Yayoi, Bunkyo-ku 113-8657 Tokyo Japan.
Rulan BaiLaboratory of Theriogenology and Animal Breeding, Graduate School of Agricultural and Life SciencesThe University of Tokyo1-1-1 Yayoi, Bunkyo-ku 113-8657 Tokyo Japan.
Hiroshi FujiwaraDepartment of Obstetrics and Gynecology, Graduate School of Medicine Science Kanazawa University 920-1192 Kanazawa Japan.
Kazuya KusamaLaboratory of Theriogenology and Animal Breeding, Graduate School of Agricultural and Life SciencesThe University of Tokyo1-1-1 Yayoi, Bunkyo-ku 113-8657 Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Processes of conceptus implantation and placentation, unique to mammalian reproduction, have been extensively studied. It was once thought that processes of these events varied greatly, notably between invasive and noninvasive modes of implantation and/or placentation. Regardless of the mode of implantation, however, physiological and biochemical processes in conceptus implantation to the maternal endometrium including the kinds of gene expression and their products are now considered not to differ so much. Recent progress has identified that in addition to the hormones, cytokines, proteases and cell adhesion molecules classically characterized, epithelial-mesenchymal transition, molecules related to lymphocyte homing, the expression of endogenous retroviruses and possibly exosomes are all required for the progression of conceptus implantation to placentation. In this review, therefore, new findings related to these events are integrated into the context of conceptus implantation to the maternal endometrium.

Indexed as

EMTERVExosomeGene expressionImplantation

Identifiers

PMID29259417
PMCPMC5715838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.