Evidence map›Paper›PMID 29259378›Full record

ArticleWorld journal of gastroenterology2017

Impact of homogeneous pathologic response to preoperative chemotherapy in patients with multiple colorectal liver metastases.

Charles Sabbagh, Denis Chatelain, Christophe Attencourt, Jean-Paul Joly, Bruno Chauffert, Cyril Cosse, Jean-Marc Regimbeau

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Charles SabbaghDepartment of Digestive and Oncologic Surgery, Amiens University Medical Center, 80054 Amiens, France.
Denis ChatelainUniversity of Picardie, 80054 Amiens, France.
Christophe AttencourtDepartment of Anatomic Pathology, Amiens University Medical Center, 80054 Amiens, France.
Jean-Paul JolyDepartment of Hepatogastroenterology, Amiens University Medical Center, 80054 Amiens, France.
Bruno ChauffertUniversity of Picardie, 80054 Amiens, France.
Cyril CosseDepartment of Digestive and Oncologic Surgery, Amiens University Medical Center, 80054 Amiens, France.
Jean-Marc RegimbeauDepartment of Digestive and Oncologic Surgery, Amiens University Medical Center, 80054 Amiens, France.
Inserm · FRUniversité de Picardie Jules Verne · FRCentre Hospitalier Universitaire Amiens-Picardie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the homogeneity of pathologic response to preoperative chemotherapy (PRPC) after chemotherapy in patients with multiple liver metastases (LM).

methodsFrom September 2011 to August 2014, patients with at least two LM undergoing preoperative chemotherapy prior to resection were included in this retrospective, single-center study. The endpoints were PRPC homogeneity (according to both the Rubbia-Brandt and MD Anderson classifications), the impact of PRPC on the MDT decision, factors associated with homogeneous PRPC and overall survival of patients with

resultsseventy-three patients with a total of 88 liver resections (including 15 two-stage procedures) were included in the study. The homogeneous PRPC rate was 55% according to the Rubbia-Brandt classification and 53% according to the MD Anderson classification. The MDT decision was modified by the PRPC in only 2.7% of patients (

conclusionThe PRPC was homogeneous in only one half of patients and had very little influence on the MDT decision.

Indexed as

AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsClinical Decision-MakingColorectal NeoplasmsFemaleHepatectomyHumansLiverLiver NeoplasmsMaleMiddle AgedNeoadjuvant TherapyPatient Care TeamResponse Evaluation Criteria in Solid TumorsColorectal cancerHomogeneityLiver metastasesPathological responsePreoperative chemotherapy

Identifiers

PMID29259378
PMCPMC5725297
OpenAlexW2772901113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.