Evidence map›Paper›PMID 29259309›Full record

ArticleScientific reports2017

Nanoconfined water can orient and cause long-range dipolar interactions with biomolecules.

Dirk Hegemann, Nicolas Hocquard, Manfred Heuberger

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dirk HegemannEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland. dirk.hegemann@empa.ch.ORCID 0000-0003-4226-9326
Nicolas HocquardEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland.
Manfred HeubergerEmpa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland. manfred.heuberger@empa.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface properties are generally determined by the top most surface layer also defining how molecules adsorb onto it. By exploring effects due to interactions with deeper subsurface layers, however, long-range interaction forces were found to also significantly contribute to molecular adsorption, in which hydration of the subsurface region is the key factor. Water molecules confined to a subsurface amphiphilic gradient are confirmed to cause these long-range dipolar interactions by preferential orientation, thus significantly changing the way how a protein interacts with the surface. These findings imply future exploitation of an additional factor to modulate adsorption processes.

Indexed as

AdsorptionSurface PropertiesWaterWater

Identifiers

PMID29259309
PMCPMC5736754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.