ArticleScientific reports2017
Comparison between Listeria sensu stricto and Listeria sensu lato strains identifies novel determinants involved in infection.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Review
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- Phylogenomic analyses of the Listeriaceae family support species reclassification and proposal of a new family and new genera.Antonie van Leeuwenhoek · 2024Article
- Aquatic environment drives the emergence of cell wall-deficient dormant forms in Listeria.Nature communications · 2024Article
- In Vitro Utilization of Prebiotics byMicroorganisms · 2024Article
- Microbiota Analysis of Ejaculated Honey Bee Drone Semen and the Effect of Semen Collection Method on Bacterial Loads.Insects · 2024Article
- Characterization of an Autoinducing Peptide Signal Reveals Highly Efficacious Synthetic Inhibitors and Activators of Quorum Sensing and Biofilm Formation inBiochemistry · 2023Article
- Whole-genome sequencing ofFrontiers in microbiology · 2023Article
- A Systematic Review ofFoods (Basel, Switzerland) · 2021Review
- A diet-specific microbiota drives Salmonella Typhimurium to adapt its in vivo response to plant-derived substrates.Animal microbiome · 2021Article
- The Opposing Role of Propionate in ModulatingFrontiers in microbiology · 2021Article
- A Survey of Bacterial Microcompartment Distribution in the Human Microbiome.Frontiers in microbiology · 2021Review
- Neurotropic Lineage III Strains of Listeria monocytogenes Disseminate to the Brain without Reaching High Titer in the Blood.mSphere · 2020Article
- The Cobalamin-Dependent Gene Cluster ofFrontiers in microbiology · 2020Review
- Article
- The σRNA biology · 2019Article
- Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection.Microbiology and molecular biology reviews : MMBR · 2019Review
- Bacterial Microcompartment-Dependent 1,2-Propanediol Utilization Stimulates Anaerobic Growth ofFrontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human pathogen L. monocytogenes and the animal pathogen L. ivanovii, together with four other species isolated from symptom-free animals, form the "Listeria sensu stricto" clade. The members of the second clade, "Listeria sensu lato", are believed to be solely environmental bacteria without the ability to colonize mammalian hosts. To identify novel determinants that contribute to infection by L. monocytogenes, the causative agent of the foodborne disease listeriosis, we performed a genome comparison of the two clades and found 151 candidate genes that are conserved in the Listeria sensu stricto species. Two factors were investigated further in vitro and in vivo. A mutant lacking an ATP-binding cassette transporter exhibited defective adhesion and invasion of human Caco-2 cells. Using a mouse model of foodborne L. monocytogenes infection, a reduced number of the mutant strain compared to the parental strain was observed in the small intestine and the liver. Another mutant with a defective 1,2-propanediol degradation pathway showed reduced persistence in the stool of infected mice, suggesting a role of 1,2-propanediol as a carbon and energy source of listeriae during infection. These findings reveal the relevance of novel factors for the colonization process of L. monocytogenes.
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