ArticleScientific reports2017
Adaptation of Stability during Perturbed Walking in Parkinson's Disease.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Use of the margin of stability to quantify stability in pathologic gait - a qualitative systematic review.BMC musculoskeletal disorders · 2021Pooled it
- Repeated Gait Perturbation Training in Parkinson's Disease and Healthy Older Adults: A Systematic Review and Meta-Analysis.Frontiers in human neuroscience · 2021Pooled it
- Perturbation-Based Balance Exercise Using a Wearable Device to Improve Reactive Postural Control.IEEE journal of translational engineering in health and medicine · 2023Trial
- Effects of repeated waist-pull perturbations on gait stability in subjects with cerebellar ataxia.Journal of neuroengineering and rehabilitation · 2019Trial
- A robotic perturbation trainer for transverse-plane gait perturbations in pediatric cerebral palsyMethodsX · 2026Article
- Reduced Effective Postural Responses to External Perturbations in Chronic Ankle Instability.Scandinavian journal of medicine & science in sports · 2026Article
- Assessment of Fall Risk in Neurological Disorders and Technology: Relationship Between Silver Index and Gait Analysis.Sensors (Basel, Switzerland) · 2026Article
- Distinct patterns in neuromuscular adaptation to repeated perturbations in chronic ankle instability.Journal of neuroengineering and rehabilitation · 2025Article
- Combined effects of Tai-Chi gait with mediolateral ground support perturbation on dynamic balance control.Sports medicine and health science · 2025Article
- Gait Instability and Compensatory Mechanisms in Parkinson's Disease Patients With Camptocormia: An Exploratory Study.Journal of movement disorders · 2025Article
- Advancing Gait Rehabilitation: A Systematic Review of Robotic Exoskeletons for Cerebral Palsy.Wearable technologies · 2025Review
- Gait alterations in patients with adult spinal deformity.North American Spine Society journal · 2024Article
- Soft robotic apparel to avert freezing of gait in Parkinson's disease.Nature medicine · 2024Article
- Article
- Age affects the dynamic interaction between kinematics and gait stability.Frontiers in bioengineering and biotechnology · 2024Article
- Margins of postural stability in Parkinson's disease: an application of control theory.Frontiers in bioengineering and biotechnology · 2023Article
- Effects of protective step training on proactive and reactive motor adaptations in Parkinson's disease patients.Frontiers in neurology · 2023Article
- Perturbation-based balance training: Principles, mechanisms and implementation in clinical practice.Frontiers in sports and active living · 2022Review
- Kinect V2-Based Gait Analysis for Children with Cerebral Palsy: Validity and Reliability of Spatial Margin of Stability and Spatiotemporal Variables.Sensors (Basel, Switzerland) · 2021Article
- Uncontrolled manifold analysis of the effects of a perturbation-based training on the organization of leg joint variance in cerebellar ataxia.Experimental brain research · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Gait and balance disorders are major problems that contribute to falls among subjects with Parkinson's disease (PD). Strengthening the compensatory responses through the use of balance perturbations may improve balance in PD. To date, it is unclear how PD affects the ability to react and adapt to perturbations delivered while walking. This study aims to investigate how PD affects the ability to walk, respond to balance perturbations, and produce acute short-term effects to improve compensatory reactions and gait stability. A cable-driven robot was used to train nine patients with PD and nine age-matched controls with multidirectional waist-pull perturbations while walking on a treadmill. Margin of stability and base of support were evaluated while walking without cables and reacting to the perturbations. PD was associated with a reduced stability in the forward direction and the inability to produce proactive anticipatory adjustments. Both groups were able to improve the response to the disturbances and produce short-term aftereffects of increased gait stability once the cables were removed. A single session of perturbation-based balance training produced acute effects that ameliorated gait instability in PD. This result is encouraging for designing new therapeutic interventions that remediate falls risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.