Evidence map›Paper›PMID 29259218›Full record

ArticleScientific reports2017

No Evidence that Knops Blood Group Polymorphisms Affect Complement Receptor 1 Clustering on Erythrocytes.

O V Swann, E M Harrison, D H Opi, E Nyatichi, A Macharia, S Uyoga, T N Williams, J A Rowe

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

O V SwannCentre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
E M HarrisonClinical Surgery, University of Edinburgh, Edinburgh, UK.
D H OpiCentre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
E NyatichiWellcome Trust Research Laboratories/Kenya Medical Research Institute, Centre for Geographic Medicine Research, Kilifi, Kenya.
A MachariaWellcome Trust Research Laboratories/Kenya Medical Research Institute, Centre for Geographic Medicine Research, Kilifi, Kenya.
S UyogaWellcome Trust Research Laboratories/Kenya Medical Research Institute, Centre for Geographic Medicine Research, Kilifi, Kenya.
T N WilliamsWellcome Trust Research Laboratories/Kenya Medical Research Institute, Centre for Geographic Medicine Research, Kilifi, Kenya.
J A RoweCentre for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK. alex.rowe@ed.ac.uk.ORCID 0000-0002-7702-1892
Kenya Medical Research Institute · KECentre for Immunity, Infection and Evolution · GBBurnet Institute · AUUniversity of Edinburgh · GB

Funding

Wellcome TrustWellcome Trust 084226Wellcome Trust 091758Wellcome Trust 101910
6 · The paper itself

Abstract

Clustering of Complement Receptor 1 (CR1) in the erythrocyte membrane is important for immune-complex transfer and clearance. CR1 contains the Knops blood group antigens, including the antithetical pairs Swain-Langley 1 and 2 (Sl1 and Sl2) and McCoy a and b (McC

Indexed as

Blood Group AntigensChildCluster AnalysisErythrocyte MembraneErythrocytesFemaleGene DosageGenotypeHumansKenyaMalePolymorphism, GeneticReceptors, Complement 3bBlood Group AntigensCR1 protein, humanReceptors, Complement 3b

Identifiers

PMID29259218
PMCPMC5736761
OpenAlexW2771566422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.