Evidence map›Paper›PMID 29259127›Full record

ArticleThe Journal of biological chemistry2018

Activated heterotrimeric G protein α

Jesi Y To, Alan V Smrcka

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. A network of GαScience signaling · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jesi Y ToFrom the Department of Pharmacology and Physiology, University of Rochester School of Medicine, Rochester, New York, 14623 and.
Alan V SmrckaFrom the Department of Pharmacology and Physiology, University of Rochester School of Medicine, Rochester, New York, 14623 and avsmrcka@umich.edu.
University of Michigan–Ann Arbor · USUniversity of Rochester · US

Funding

Selective Targeting of G Protein beta gamma Subunits with Small MoleculesR01GM081772 · NIGMS · UNIVERSITY OF ROCHESTER · PI SMRCKA, ALAN V. · 2008 to 2017
$3.2M
NIGMS NIH HHS R01 GM081772
6 · The paper itself

Abstract

Our recent work uncovered novel roles for activated Gα

Indexed as

Cell MovementMutation, MissenseAmino Acid SubstitutionCarrier ProteinsCell AdhesionFibronectinsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsHL-60 CellsHumansrap1 GTP-Binding ProteinsCarrier ProteinsFibronectinsGNAI1 protein, humanGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsRADIL protein, humanRAP1A protein, humanrap1 GTP-Binding Proteinsadhesioncell migrationcell signalingchemokinesG proteinG protein–coupled receptor (GPCR)integrin

Identifiers

PMID29259127
PMCPMC5798289
OpenAlexW2777071929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.