Evidence map›Paper›PMID 29259077›Full record

ArticlePediatrics2018

BMI Trajectories Associated With Resolution of Elevated Youth BMI and Incident Adult Obesity.

Marie-Jeanne Buscot, Russell J Thomson, Markus Juonala, Matthew A Sabin, David P Burgner, Terho Lehtimäki, Nina Hutri-Kähönen, Jorma S A Viikari, Eero Jokinen, Paivi Tossavainen and 3 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Diet, adiposity, and the gut microbiota from infancy to adolescence: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  2. Pooled it
  3. Trial
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  5. Review
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  7. The role of probiotics in adolescents' obesity.Frontiers in cellular and infection microbiology · 2025
    Review
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  9. Article
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  11. Article
  12. Article
  13. Article
  14. Article
  15. Health Impacts of High BMI in China: Terrible Present and Future.International journal of environmental research and public health · 2022
    Article
  16. Article
  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Marie-Jeanne BuscotMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia; m.buscot@utas.edu.au.
Russell J ThomsonCentre for Research in Mathematics, School of Computing, Engineering and Mathematics, Western Sydney University, Sydney, New South Wales, Australia.
Markus JuonalaResearch Centre of Applied and Preventive Cardiovascular Medicine and.
Matthew A SabinMurdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
David P BurgnerMurdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
Terho LehtimäkiFimlab Laboratories Ltd, Tampere, Finland.
Nina Hutri-KähönenPediatrics, Faculty of Medicine and Life Sciences, University of Tampere and Tampere University Hospital, Tampere, Finland.
Jorma S A ViikariDepartments of Medicine and.
Eero JokinenDepartment of Pediatric Cardiology, Hospital for Children and Adolescents and University of Helsinki, Helsinki, Finland.
Paivi TossavainenDepartment of Pediatrics, PEDEGO Research Unit and Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland; and.
Tomi LaitinenDepartment of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.
Olli T RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine and.
Costan G MagnussenMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesYouth with high BMI who become nonobese adults have the same cardiovascular risk factor burden as those who were never obese. However, the early-life BMI trajectories for overweight or obese youth who avoid becoming obese adults have not been described. We aimed to determine and compare the young-childhood BMI trajectories of participants according to their BMI status in youth and adulthood.

methodsBayesian hierarchical piecewise regression modeling was used to analyze the BMI trajectories of 2717 young adults who had up to 8 measures of BMI from childhood (ages 3-18 years) to adulthood (ages 34-49 years).

resultsCompared with those with persistently high BMI, those who resolved their high youth BMI by adulthood had lower average BMI at age 6 years and slower rates of BMI change from young childhood. In addition, their BMI levels started to plateau at 16 years old for females and 21 years old for males, whereas the BMI of those whose high BMI persisted did not stabilize until 25 years old for male subjects and 27 years for female subjects. Compared with those youth who were not overweight or obese and who remained nonobese in adulthood, those who developed obesity had a higher BMI rate of change from 6 years old, and their BMI continued to increase linearly until age 30 years.

conclusionsEfforts to alter BMI trajectories for adult obesity should ideally commence before age 6 years. The natural resolution of high BMI starts in adolescence for males and early adulthood for females, suggesting a critical window for secondary prevention.

Indexed as

Body Mass IndexBody-Weight TrajectoryAdolescentAdultAge DistributionBayes TheoremChildCohort StudiesFemaleFinlandHumansIncidenceMaleMiddle AgedOverweightPediatric Obesity

Identifiers

PMID29259077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.