Evidence map›Paper›PMID 29259064›Full record

ArticleBMJ open2017

Bleeding risk in patients using oral anticoagulants submitted to surgical procedures in dentistry: a systematic review protocol.

Rogério Heládio Lopes Motta, Cristiane de Cássia Bergamaschi, Natalia Karol de Andrade, Caio Chaves Guimaraes, Juliana Cama Ramacciato, Jimmy de Oliveira Araújo, Luciane Cruz Lopes

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rogério Heládio Lopes MottaPharmacology, Anesthesiology and Therapeutics, São Leopoldo Mandic Dental School and Research Center, Campinas, São Paulo, Brazil.
Cristiane de Cássia BergamaschiDepartment of Pharmaceutical Sciences Graduate Program, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Natalia Karol de AndradePharmacology, Anesthesiology and Therapeutics, São Leopoldo Mandic Dental School and Research Center, Campinas, São Paulo, Brazil.
Caio Chaves GuimaraesPharmacology, Anesthesiology and Therapeutics, São Leopoldo Mandic Dental School and Research Center, Campinas, São Paulo, Brazil.
Juliana Cama RamacciatoPharmacology, Anesthesiology and Therapeutics, São Leopoldo Mandic Dental School and Research Center, Campinas, São Paulo, Brazil.
Jimmy de Oliveira AraújoPharmacology, Anesthesiology and Therapeutics, São Leopoldo Mandic Dental School and Research Center, Campinas, São Paulo, Brazil.
Luciane Cruz LopesDepartment of Pharmaceutical Sciences Graduate Program, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Faculdade São Leopoldo Mandic · BRUniversidade de Sorocaba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe management of patients undergoing oral surgical procedures using anticoagulants raises concerns regarding the risk of bleeding. Bleeding rates in those patients during or after oral surgical procedures are uncertain. The aim of this study will be to determine the bleeding rate during and after oral surgeries in patients using anticoagulants. METHODS AND ANALYSIS: A systematic review will be conducted and if appropriate, a meta-analysis of randomised clinical trials evaluating the bleeding risk during and after oral surgical procedures in patients using anticoagulants were selected. The literature search will be conducted using electronic databases, such as the Cochrane Central Register of Controlled Trials, MEDLINE (via Ovid), Embase (via Ovid), Cumulative Index to Nursing and Allied Health Literature (via Ovid), LILACS (SciELO) and CAPES database, without restriction of languages or date of publication. The primary outcome will be the occurrence of local bleeding rate during and after oral surgical procedures, and as secondary outcome, the following complications will be considered: implant failure, healing problems and infections. Groups of two independent reviewers will select the titles and abstracts for full-text eligibility. For eligible studies, the same reviewers will perform data extraction, bias risk assessment and determination of the overall quality of evidence for each of the outcomes using the Grading of Recommendations Assessment, Development and Evaluation classification system. Meta-analysis and subgroup analyses will be conducted, to all outcomes, if appropriate. ETHICS AND DISSEMINATION: The systematic review will be published in a peer-reviewed journal, and brief reports of the review's findings will be released directly to the intended audience. The results will help dentists in the decision-making process to minimise the risk of bleeding in patients using anticoagulants in their clinical practice. PROSPERO REGISTRATION NUMBER: CRD42017056986.

Indexed as

Administration, OralAnticoagulantsHemorrhageHumansMeta-Analysis as TopicOral Surgical ProceduresPostoperative ComplicationsRandomized Controlled Trials as TopicResearch DesignRisk AssessmentSystematic Reviews as TopicAnticoagulantsanticoagulantsbleedingoral surgerysystematic review

Identifiers

PMID29259064
PMCPMC5778277
OpenAlexW2780266880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.