Evidence map›Paper›PMID 29259003›Full record

ArticleBlood2018

Normal plasma IgG inhibits HIT antibody-mediated platelet activation: implications for therapeutic plasma exchange.

Curtis G Jones, Shannon M Pechauer, Brian R Curtis, Daniel W Bougie, Richard H Aster, Anand Padmanabhan

Abstract readLetter
In one paragraph

Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Demystifying autoimmune HIT: what it is, when to test, and how to treat.Hematology. American Society of Hematology. Education Program · 2024
    Review
  4. Approaches to management of HIT in complex scenarios, including cardiac surgery.Hematology. American Society of Hematology. Education Program · 2024
    Review
  5. Article
  6. Autoimmune Heparin-Induced Thrombocytopenia.Journal of clinical medicine · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Curtis G JonesMedical Sciences Institute.
Shannon M PechauerBlood Research Institute, and.
Brian R CurtisPlatelet and Neutrophil Immunology Laboratory, Blood Center of Wisconsin, Milwaukee, WI; and.
Daniel W BougieBlood Research Institute, and.
Richard H AsterBlood Research Institute, and.
Anand PadmanabhanMedical Sciences Institute.

Funding

HEMORRHAGIC DISEASESR01HL013629 · NHLBI · VERSITI WISCONSIN, INC. · PI ASTER, RICHARD HERBERT · 1985 to 2019
$8.7M
New Approaches to Pathogenesis and Diagnosis of Heparin-Induced Thrombocytopenia (HIT)K08HL133479 · NHLBI · VERSITI WISCONSIN, INC. · PI PADMANABHAN, ANAND · 2017 to 2021
$836k
NHLBI NIH HHS K08 HL133479NHLBI NIH HHS R01 HL013629
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Platelet ActivationAntibodiesHeparinHumansImmunoglobulin GPlasma ExchangePlatelet Factor 4ThrombocytopeniaAntibodiesHeparinImmunoglobulin GPlatelet Factor 4

Identifiers

PMID29259003
PMCPMC5805490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.