Evidence map›Paper›PMID 29258916›Full record

ReviewPharmacological research2018

Potential of selected Lamiaceae plants in anti(retro)viral therapy.

Maja Bekut, Snežana Brkić, Nebojša Kladar, Gordana Dragović, Neda Gavarić, Biljana Božin

Abstract readReview
In one paragraph

Review in Pharmacological research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. [Herbal treatment options for post-viral symptoms and long COVID].Wiener medizinische Wochenschrift (1946) · 2026
    Review
  4. Plants (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Antiviral Activity ofBiomedicines · 2025
    Article
  9. Review
  10. Phytochemical and Pharmacological Insights intoMolecules (Basel, Switzerland) · 2025
    Review
  11. Evaluation ofPeerJ · 2025
    Article
  12. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  13. Biology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maja BekutUniversity of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000 Novi Sad, Serbia. Electronic address: maja.bekut@mf.uns.ac.rs.
Snežana BrkićUniversity of Novi Sad, Faculty of Medicine, Department of Infectious Diseases, Hajduk Veljkova 3, 21000 Novi Sad, Serbia; Clinical Centre of Vojvodina, Clinic for Infectious Diseases, Hajduk Veljkova 1, 21000 Novi Sad, Serbia.
Nebojša KladarUniversity of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Gordana DragovićUniversity of Belgrade, School of Medicine, Department of Pharmacology, Clinical Pharmacology and Toxicology, Dr Subotica 1/III, 11000 Belgrade, Serbia.
Neda GavarićUniversity of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Biljana BožinUniversity of Novi Sad, Faculty of Medicine, Department of Pharmacy, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constant search for new drugs with antiviral properties often extends to products of natural origin. Lamiaceae is one of the most important herbal families, well known for various biological and medicinal effects of a variety of aromatic spices, including thyme, mint, oregano, basil, sage, savory, rosemary, self-heal, hyssop, lemon balm and many others. The paper provides a review of antiviral potential of previously mentioned plants which has been demonstrated so far, with special emphasis on anti-HIV properties. Relevant articles were compiled by searching plant names combined with keywords describing antiviral activity. The antiviral effect is direct, with prominent activity against enveloped viral species. Initial stages of the viral life cycle are the most affected, as these plants appear to be targeting mainly viral structures responsible for attachment to target cells. In case of HIV, there is some activity against key enzymes in the viral life cycle. Even in the case of drug resistance, there is an equal susceptibility to applied herbal preparations. Some in vivo experiments suggest that use of Lamiaceae representatives could help in prevention and treatment of some viral diseases. A possible reduction of side effects of diseases and conventional drug therapy are also some aspects worth further investigations.

Indexed as

LamiaceaePhytotherapyAnimalsAntiviral AgentsHumansPhytochemicalsPlant PreparationsVirus DiseasesAntiviral AgentsPhytochemicalsPlant PreparationsAnti-HIVAntiretroviralAntiviralHerbsLamicaeae

Identifiers

PMID29258916
PMCPMC7129285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.