Evidence map›Paper›PMID 29258604›Full record

Observational studyJournal of translational medicine2017

Water T

Michelle D Robinson, Ina Mishra, Sneha Deodhar, Vipulkumar Patel, Katrina V Gordon, Raul Vintimilla, Kim Brown, Leigh Johnson, Sid O'Bryant, David P Cistola

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Early detection of metabolic dysregulation using water TDiabetes, metabolic syndrome and obesity : targets and therapy · 2018
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michelle D RobinsonNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Ina MishraNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Sneha DeodharNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Vipulkumar PatelNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Katrina V GordonNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Raul VintimillaCenter for Alzheimer's & Neurodegenerative Diseases Research, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Kim BrownCenter for Alzheimer's & Neurodegenerative Diseases Research, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Leigh JohnsonCenter for Alzheimer's & Neurodegenerative Diseases Research, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Sid O'BryantCenter for Alzheimer's & Neurodegenerative Diseases Research, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
David P CistolaNanoparticle Diagnostics Laboratory, Institute for Cardiovascular & Metabolic Diseases, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA. david.cistola@ttuhsc.edu.
University of North Texas · USUniversity of North Texas Health Science Center · US

Funding

A Blood-Based Screening Tool for Alzheimer's DiseaseR01AG039389 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI O'BRYANT, SID E · 2012 to 2013
$608k
NIA NIH HHS R01 AG039389NIA NIH HHS R01AG039389
6 · The paper itself

Abstract

backgroundMetabolic syndrome (MetS) is a highly prevalent condition that identifies individuals at risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. Prevention of these diseases relies on early detection and intervention in order to preserve pancreatic β-cells and arterial wall integrity. Yet, the clinical criteria for MetS are insensitive to the early-stage insulin resistance, inflammation, cholesterol and clotting factor abnormalities that characterize the progression toward type 2 diabetes and atherosclerosis. Here we report the discovery and initial characterization of an atypical new biomarker that detects these early conditions with just one measurement.

methodsWater T

resultsPlasma and serum water T

conclusionsWater T

Indexed as

Magnetic Resonance SpectroscopyAdultAgedAged, 80 and overBiomarkersBlood ProteinsCluster AnalysisCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMetabolic SyndromeMiddle AgedPrincipal Component AnalysisROC CurveBiomarkersBlood ProteinsWaterAtherosclerosis, cardiovascular diseaseInflammation, dyslipidemia, magnetic resonance relaxometryInsulin resistanceMetabolic syndromeT2, transverse relaxation time, type 2 diabetes mellitus

Identifiers

PMID29258604
PMCPMC5738216
OpenAlexW2777658707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.