ReviewBMC systems biology2017
Systems healthcare: a holistic paradigm for tomorrow.
Review in BMC systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Review
- Outcome centred process mapping in healthcare using random forest and process mining.Scientific reports · 2025Article
- Analysis of a theory of change to evaluate the Health Care-Associated Infection Prevention Program (HAI) in Colombia.BMC health services research · 2025Article
- The Indirect Effect of an Internet-Based Intervention on Third-Party Disability for Significant Others of Individuals with Tinnitus.Audiology research · 2024Article
- Unravelling the gut-lung axis: insights into microbiome interactions and Traditional Indian Medicine's perspective on optimal health.FEMS microbiology ecology · 2023Review
- Oxidative Stress in Type 2 Diabetes: The Case for Future Pediatric Redoxomics Studies.Antioxidants (Basel, Switzerland) · 2022Review
- Review
- Managing the Built Environment for Health Promotion and Disease Prevention With Maharishi Vastu Architecture: A Review.Global advances in health and medicine · 2022Article
- A Vision of Future Healthcare: Potential Opportunities and Risks of Systems Medicine from a Citizen and Patient Perspective-Results of a Qualitative Study.International journal of environmental research and public health · 2021Article
- Role of antioxidants and a nutrient rich diet in Alzheimer's disease.Open biology · 2020Review
- Kaempferol Treatment after Traumatic Brain Injury during Early Development Mitigates Brain Parenchymal Microstructure and Neural Functional Connectivity Deterioration at Adolescence.Journal of neurotrauma · 2020Article
- Living With COVID-19: A Systemic and Multi-Criteria Approach to Enact Evidence-Based Health Policy.Frontiers in public health · 2020Article
- Clinical Applications of System Regulation Medicine.Open access Macedonian journal of medical sciences · 2019Review
- Plasma microRNA markers of upper limb recovery following human stroke.Scientific reports · 2018Article
- Addressing Clinician Burnout: A Unifying Systems Medicine Model with Meditation as a Heart-mind Intervention.Heart and mind (Mumbai, India)Article
- Prakriti phenotypes as a stratifier of gut microbiome: A new frontier in personalized medicine?Journal of Ayurveda and integrative medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Systems healthcare is a holistic approach to health premised on systems biology and medicine. The approach integrates data from molecules, cells, organs, the individual, families, communities, and the natural and man-made environment. Both extrinsic and intrinsic influences constantly challenge the biological networks associated with wellness. Such influences may dysregulate networks and allow pathobiology to evolve, resulting in early clinical presentation that requires astute assessment and timely intervention for successful mitigation. Herein, we describe the components of relevant biological systems and the nature of progression from at-risk to manifest disease. We illustrate the systems approach by examining two relevant clinical examples: Alzheimer's and cardiovascular diseases. The implications of systems healthcare management are examined through the lens of economics, ethics, policy and the law. Finally, we propose the need to develop new educational paradigms to enhance the training of the health professional in an era of systems medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.