Evidence map›Paper›PMID 29258283›Full record

ArticleInternational journal of molecular sciences2017

Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice.

Yung-Cheng Huang, Huey-Jen Tsay, Mei-Kuang Lu, Chien-Hung Lin, Chih-Wen Yeh, Hui-Kang Liu, Young-Ji Shiao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Pooled it
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  5. RoastedAntioxidants (Basel, Switzerland) · 2025
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  6. Research Progress on Chemical Components ofMolecules (Basel, Switzerland) · 2025
    Review
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  8. Review
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  10. Bioactive components and clinical potential ofFrontiers in pharmacology · 2025
    Review
  11. Review ofChinese herbal medicines · 2025
    Review
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Yung-Cheng HuangDepartment of Physical Medicine and Rehabilitation, Cheng Hsin General Hospital, Taipei 11220, Taiwan. jeremy0681@gmail.com.
Huey-Jen TsayInstitute of Neuroscience, Brain Research Center, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan.
Mei-Kuang LuNational Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 11221, Taiwan. mklu@nricm.edu.tw.
Chien-Hung LinInstitute of Neuroscience, Brain Research Center, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan. hjtsay@ym.edu.tw.
Chih-Wen YehInstitute of Neuroscience, Brain Research Center, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan. whitebrake@hotmail.com.
Hui-Kang LiuNational Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 11221, Taiwan. hk.liu@nricm.edu.tw.
Young-Ji ShiaoNational Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 11221, Taiwan. yshiao@nricm.edu.tw.ORCID 0000-0002-2699-116X
National Yang Ming Chiao Tung University · TWMinistry of Health and Welfare · KRNational Research Institute of Chinese Medicine · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAnimalsAstragalus propinquusBrainCognitive DysfunctionFatty LiverFemaleMaleMiceObesityPolysaccharidesPolysaccharidesAlzheimer’s diseaseamyloid plaqueAstragalus-polysaccharidescognitive dysfunctiongliametabolic stresses

Identifiers

PMID29258283
PMCPMC5751345
OpenAlexW2780295374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.