Evidence map›Paper›PMID 29258243›Full record

ArticleInternational journal of molecular sciences2017

Canadine from Corydalis turtschaninovii Stimulates Myoblast Differentiation and Protects against Myotube Atrophy.

Heyjin Lee, Sang-Jin Lee, Gyu-Un Bae, Nam-In Baek, Jae-Ha Ryu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Corylifol A fromInternational journal of molecular sciences · 2020
    Article
  7. Effects of conditioned media from murine lung cancer cells and human tumor cells on cultured myotubes.American journal of physiology. Endocrinology and metabolism · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Heyjin LeeResearch Center for Cell Fate Control and College of Pharmacy, Sookmyung Women's University, 100 Chungparo 47-Gil, Yongsan-Gu, Seoul 04310, Korea. u9698115@naver.com.
Sang-Jin LeeResearch Center for Cell Fate Control and College of Pharmacy, Sookmyung Women's University, 100 Chungparo 47-Gil, Yongsan-Gu, Seoul 04310, Korea.
Gyu-Un BaeResearch Center for Cell Fate Control and College of Pharmacy, Sookmyung Women's University, 100 Chungparo 47-Gil, Yongsan-Gu, Seoul 04310, Korea. lee.sangjin74@gmail.com.
Nam-In BaekThe Graduate School of Biotechnology, Kyung Hee University, Yongin, Gyeonggi 17104, Korea. nibaek@khu.ac.kr.
Jae-Ha RyuResearch Center for Cell Fate Control and College of Pharmacy, Sookmyung Women's University, 100 Chungparo 47-Gil, Yongsan-Gu, Seoul 04310, Korea. ryuha@sookmyung.ac.kr.
Sookmyung Women's University · KRKyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cachexia and sarcopenia are the main causes of muscle atrophy. These result in a reduction in the muscle fiber area, myo-protein content, and muscle strength, with various molecular modulators being involved. Although several reports have proposed potential therapeutic agents, no effective treatments have been found for muscle atrophy. We searched for myogenic modulators from medicinal plants to treat muscle diseases. We isolated six alkaloids from

Indexed as

AnimalsBerberineCell DifferentiationCell Line, TumorCorydalisMiceMuscular AtrophyMyoblastsMyoD Proteinp38 Mitogen-Activated Protein KinasesUbiquitin-Protein LigasesBerberinecanadineMyoD Proteinp38 Mitogen-Activated Protein KinasesUbiquitin-Protein LigasescanadineCorydalis turtschaninoviiisoquinoline alkaloidmuscle atrophymyoblast differentiation

Identifiers

PMID29258243
PMCPMC5751347
OpenAlexW2777678193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.