Acid-Induced Rearrangement of Epoxygermacranolides: Synthesis of Furanoheliangolides and Cadinanes from Nobilin.

Maria De Mieri, Martin Smieško, Isidor Ismajili, Marcel Kaiser, Matthias Hamburger

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 82% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria De MieriPharmaceutical Biology, Pharmazentrum, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. mariademieri@gmail.com.

Martin SmieškoMolecular Modeling, Pharmazentrum, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. martin.smiesko@unibas.ch.ORCID 0000-0003-2758-2680

Isidor IsmajiliPharmaceutical Biology, Pharmazentrum, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. isidor.ismajili@gmail.com.

Marcel KaiserDepartment of Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4000 Basel, Switzerland. marcel.kaiser@swisstph.ch.

Matthias HamburgerPharmaceutical Biology, Pharmazentrum, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. Matthias.Hamburger@unibas.ch.ORCID 0000-0001-9331-273X

University of Basel · CHSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acid-induced rearrangement of three epoxyderivatives of nobilin

Indexed as

Antiprotozoal AgentsBridged-Ring CompoundsCatalysisChamaemelumCyclizationFuransInhibitory Concentration 50Leishmania donovaniLewis AcidsMolecular StructurePlant ExtractsPlasmodium falciparumPolycyclic SesquiterpenesSesquiterpenesSesquiterpenes, GermacraneSesterterpenesAntiprotozoal AgentsBridged-Ring CompoundscadinanefuranoheliangolideFuransLewis AcidsPlant ExtractsPolycyclic SesquiterpenesSesquiterpenesSesquiterpenes, GermacraneSesterterpenesacid-catalyzed rearrangementanti-protozoal activityepoxygermacranolidesmechanism of reactionsesquiterpene lactones

Identifiers

PMID29258233

DOI10.3390/molecules22122252

PMCPMC6149915

OpenAlexW2776586296

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.