Evidence map›Paper›PMID 29258203›Full record

ArticleViruses2017

Cleavage and Structural Transitions during Maturation of Staphylococcus aureus Bacteriophage 80α and SaPI1 Capsids.

James L Kizziah, Keith A Manning, Altaira D Dearborn, Erin A Wall, Laura Klenow, Rosanne L L Hill, Michael S Spilman, Scott M Stagg, Gail E Christie, Terje Dokland

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Formation and role of the portal ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Capsid Structure ofJournal of virology · 2021
    Article
  9. Article
  10. Review
  11. Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

James L KizziahDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. kizziah4@uab.edu.ORCID 0000-0002-2608-8595
Keith A ManningDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. k1797732@uab.edu.
Altaira D DearbornProtein Expression Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, The National Institutes of Health, Bethesda, MD 20892, USA. altaira.dearborn@nih.gov.
Erin A WallDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, USA. erin.wall@nih.gov.
Laura KlenowDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, USA. laura.klenow@fda.hhs.gov.
Rosanne L L HillDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. rozythorn@gmail.com.
Michael S SpilmanInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA. mspilman@directelectron.com.
Scott M StaggInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA. sstagg@fsu.edu.
Gail E ChristieDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, USA. gail.christie@vcuhealth.org.
Terje DoklandDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. dokland@uab.edu.
University of Alabama at Birmingham · USVirginia Commonwealth University · USFlorida State University · USNational Institutes of Health · US

Funding

Structural basis for pathogenicity island mobilization in S. aureusR01AI083255 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DOKLAND, TERJE · 2009 to 2023
$5.6M
Purchase of a direct electron camera for the Titan-Krios at FSUS10OD018142 · OD · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 2014 to 2014
$384k
NIAID NIH HHS R01 AI083255NIH HHS S10 OD018142
6 · The paper itself

Abstract

In the tailed bacteriophages, DNA is packaged into spherical procapsids, leading to expansion into angular, thin-walled mature capsids. In many cases, this maturation is accompanied by cleavage of the major capsid protein (CP) and other capsid-associated proteins, including the scaffolding protein (SP) that serves as a chaperone for the assembly process.

Indexed as

Virus AssemblyCapsidCryoelectron MicroscopyMicrobial ViabilityMutationProtein ConformationStaphylococcus aureusStaphylococcus Phagescapsid size determinationCaudoviralescryo-electron microscopySaPI1Staphylococcus aureus pathogenicity islandsvirus assembly

Identifiers

PMID29258203
PMCPMC5744158
OpenAlexW2779403696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.