ReviewToxins2017
Botulinum Toxin in the Field of Dermatology: Novel Indications.
Review in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Targeting Nociceptors in Hidradenitis Suppurativa
Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is Botulinum toxin A effective in treating dry eye disease? A systematic review and meta-analysis.Eye (London, England) · 2025Pooled it
- Trial
- Real-World Use of Polynucleotide Injections in Scar Prevention and Management: A Nationwide Survey of Korean Society for Anti-Aging Dermatology (KAAD) Dermatologists.Journal of cosmetic dermatology · 2026Article
- Is Current Evidence Sufficient to Establish the Efficacy of Botulinum Toxin A in Treating Persistent Dry Eye Disease? A Systematic Review and Meta-Analysis of Interventional Studies With a Critical Review Using GRADE Tool.Health science reports · 2026Review
- Clostridium botulinum serotype B: microbial genetics, toxin biosynthesis, current applications, and future prospects.Archives of microbiology · 2025Review
- Ultrasound assessment of botulinum toxin-A (BOTOX) injection into adult Arabian dromedary camels' lips: efficacy in detection and localization.BMC veterinary research · 2025Article
- Article
- Study on botulinum toxin in dermatology from 2000 to 2023: A CiteSpace-based bibliometric analyses.Journal of cosmetic dermatology · 2024Review
- Botulinum Toxin A and B for Palmoplantar Hyperhidrosis.Dermatology and therapy · 2024Article
- Current practices and perceived effectiveness of polynucleotides for treatment of facial erythema by cosmetic physicians.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- Botulinum neurotoxins: Future innovations.Medicine · 2023Article
- [Neuropathic pruritus-Evidence-based treatment recommendations].Der Nervenarzt · 2023Review
- How Does Botulinum Toxin Inhibit Itch?Toxins · 2022Review
- Dermatological Conditions Inducing Acute and Chronic Pain.Acta dermato-venereologica · 2022Review
- Botulinum Toxin A in the Management of Acne Vulgaris: Evidence and Recommendations.Aesthetic surgery journal · 2022Article
- Botulinum Toxin Use for Modulating Neuroimmune Cutaneous Activity in Psoriasis.Medicina (Kaunas, Lithuania) · 2022Review
- Insights on Skin Quality and Clinical Practice Trends in Asia Pacific and a Practical Guide to Good Skin Quality from the Inside Out.The Journal of clinical and aesthetic dermatology · 2022Review
- [Research advances on application of botulinum toxin type A in scar prevention and treatment].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Review
- Botulinum Toxin: An Effective Treatment for Flushing and Persistent Erythema in Rosacea.The Journal of clinical and aesthetic dermatology · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since its approval by the US Food and Drug Administration in 2002 for glabellar wrinkles, botulinum toxin (BTX) has been widely used to correct facial wrinkles. As a result, many consider BTX synonymous with cosmetic dermatology. Recent studies indicate that BTX elicits biological effects on various skin cell types via the modulation of neurotransmitter release, and it seems that BTX has a wider zone of dermatologic influence than originally understood. Clinicians and researchers are now beginning to explore the potential of BTX beyond the amelioration of facial lines and encouraging results are seen with BTX in a variety of skin conditions. In this paper, we review novel dermatological indications of BTX which includes (but not limited to) scar prevention, facial flushing, post-herpetic neuralgia and itch. These areas show great promise, but there is definite need for larger, double-blinded, randomized control trials against established treatments before BTX becomes a clinical reality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.