Evidence map›Paper›PMID 29257946›Full record

ArticleDevelopmental cell2017

Probing Cilia-Associated Signaling Proteomes in Animal Evolution.

Avital S Shulman, Meng-Fu Bryan Tsou

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Avital S ShulmanCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA.
Meng-Fu Bryan TsouCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA. Electronic address: tsoum@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The Control of Centriole Duplication and DegenerationR01GM088253 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI MENG-FU BRYAN TSOU · 2009 to 2026
$6.2M
TRAINING PROGRAM IN MOLECULAR AND CELLULAR BIOLOGYT32GM008539 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BROWN, ANTHONY M.C. · 1995 to 2020
$5.0M
NIGMS NIH HHS R01 GM088253NIGMS NIH HHS T32 GM008539
6 · The paper itself

Abstract

Cilia have evolved to function as essential sensory organelles in animals. To understand why cilia are intimately associated with cell signaling, Sigg et al. (2017) develop and apply a comparative proteomics approach, reported in this issue of Developmental Cell, to analyze the evolutionary relationship between cilia and various signaling pathways.

Indexed as

CiliaProteomicsAnimalsOrganellesProteomeSignal TransductionProteome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.