ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery
BILIARY COMPLICATIONS AFTER LIVER TRANSPLANTATION.
Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 21 citations in OpenAlex.
- LIVER TRANSPLANTATION IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS: A MULTICENTRIC STUDY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023Observational
- Biliary complications in recipients of living donor liver transplantation: A single-centre study.World journal of hepatology · 2021Article
- Factors affecting anxiety, depression, and self-care ability in patients who have undergone liver transplantation.World journal of gastroenterology · 2021Article
- Cholangiocyte organoids as a cell source for biliary repair.Transplant international : official journal of the European Society for Organ Transplantation · 2021Article
- Platelet-rich fibrin can accelerate the healing of common bile duct anastomosis in a rat.Turkish journal of surgery · 2020Article
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundBiliary reconstitution has been considered the Achilles's heel of liver transplantations due to its high rate of postoperative complications.
aimTo evaluate the risk factors for occurrence of biliary strictures and leakages, and the most efficient methods for their treatment.
methodOf 310 patients who underwent liver transplantation between 2001 and 2015, 182 medical records were retrospectively analyzed. Evaluated factors included demographic profile, type of transplantation and biliary reconstitution, presence of vascular and biliary complications, their treatment and results.
results153 (84.07%) deceased donor and 29 (15.93%) living donor transplantations were performed. Biliary complications occurred in 49 patients (26.92%): 28 strictures (15.38%), 14 leakages (7.7%) and seven leakages followed by strictures (3.85%). Hepatic artery thrombosis was present in 10 patients with biliary complications (20.4%; p=0,003). Percutaneous and endoscopic interventional procedures (including balloon dilation and stent insertion) were the treatment of choice for biliary complications. In case of radiological or endoscopic treatment failure, surgical intervention was performed (biliodigestive derivation or retransplantation (32.65%). Complications occurred in 25% of patients treated with endoscopic or percutaneous procedures and in 42.86% of patients reoperated. Success was achieved in 45% of patients who underwent endoscopic or percutaneous procedures and in 61.9% of those who underwent surgery.
conclusionBiliary complications are frequent events after liver transplantation. They often require new interventions: endoscopic and percutaneous procedures at first and surgical treatment when needed. Hepatic artery thrombosis increases the number of biliary complications.
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