Trial reportClinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine2018
Safety and Prognostic Utility of Provocative Exercise Testing in Acutely Concussed Adolescents: A Randomized Trial.
Trial report in Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02959216 (Sub-Symptom Aerobic Exercise Therapy to Improve Recovery From Acute Sport-Related Concussion), which is not on this map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sub-Symptom Aerobic Exercise Therapy to Improve Recovery From Acute Sport-Related Concussion: A Randomized Controlled Trial
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review.Physiotherapy Canada. Physiotherapie Canada · 2024Pooled it
- Feasibility of superimposed supine cycling and lower body negative pressure as an effective means of prolonging exercise tolerance in individuals experiencing persisting post-concussive symptoms: Preliminary results.Experimental physiology · 2026Trial
- Symptom Exacerbation and Adverse Events During a Randomized Trial of Early-Stage Rehabilitation After Sport-Related Concussion: Safety Outcomes From the Active Rehab Study.Journal of athletic training · 2024Trial
- Implementation and Adoption of Telerehabilitation for Treating Mild Traumatic Brain Injury.Journal of neurologic physical therapy : JNPT · 2022Trial
- The acute, systemic effects of aerobic exercise in recently concussed adolescent student-athletes: preliminary findings.European journal of applied physiology · 2022Trial
- Influence of Aerobic Exercise Volume on Postconcussion Symptoms.The American journal of sports medicine · 2021Trial
- Early Subthreshold Aerobic Exercise for Sport-Related Concussion: A Randomized Clinical Trial.JAMA pediatrics · 2019Trial
- Effectiveness of a Customized Rehabilitation Program for Adults With Post-Concussion Syndrome-A Randomized Controlled Crossover Trial.The Journal of head trauma rehabilitationTrial
- Trial
- miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial.Brain injury · 2026Article
- Clinical Assessment on Days 1-14 for the Characterization of Traumatic Brain Injury: Recommendations from the 2024 NINDS Traumatic Brain Injury Classification and Nomenclature Initiative Clinical/Symptoms Working Group.Journal of neurotrauma · 2025Review
- Complexity of post-concussion syndrome assessment and management: a case for customizing rehabilitation.Biomedical engineering online · 2025Article
- Article
- Evaluating User Experience and Satisfaction in a Concussion Rehabilitation App: Usability Study.JMIR formative research · 2025Article
- Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation.CNS & neurological disorders drug targets · 2025Review
- The Clinical Utility of Assessing Orthostatic Intolerance in Adolescents with Sport-Related Concussion, a Retrospective Study.Diagnostics (Basel, Switzerland) · 2024Article
- Adaptive Approaches to Exercise Rehabilitation for Postural Tachycardia Syndrome and Related Autonomic Disorders.Archives of rehabilitation research and clinical translation · 2024Article
- The Unconsidered Pathway: Suggestions for Physical Therapists to Facilitate Student Reintegration to Physical Education after a Concussion.Children (Basel, Switzerland) · 2024Article
- Orthostatic Vital Signs After Sport-Related Concussion: A Cohort Study.The American journal of sports medicine · 2024Article
- Use of the Buffalo Concussion Treadmill Test in community adult patients with mild traumatic brain injury.PM & R : the journal of injury, function, and rehabilitation · 2024Observational
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveTo evaluate (1) systematic assessment of exercise tolerance in adolescents shortly after sport-related concussion (SRC) and (2) the prognostic utility of such assessment.
designProspective randomized controlled trial.
settingUniversity and community sports medicine centers.
participantsAdolescents with SRC (1-9 days from injury). Sixty-five were randomized and 54 completed the study (mean age 15 years, 4 days after injury).
interventionsBuffalo Concussion Treadmill Test (BCTT, n = 27) or not (controls, n = 27) on visit day #1. Heart rate threshold (HRt) at symptom exacerbation represented level of exercise tolerance. Participants reported symptoms daily for 14 days and then had follow-up BCTT (n = 54). Recovery was defined as returning to normal level of symptoms and exercise tolerance, verified by independent physician examination.
main outcome measuresDays to recovery and typical (≤21 days) versus prolonged recovery (>21 days). Mixed effects linear models and linear regression techniques examined symptom reports and time to recovery. Linear regression assessed the association of HRt with recovery time.
resultsDays to recovery (P = 0.7060) and typical versus prolonged recovery (P = 0.1195) were not significantly different between groups. Symptom severity scores decreased in both groups over 14 days (P < 0.0001), were similar (P = 0.2984), and did not significantly increase the day after the BCTT (P = 0.1960). Lower HRt on visit day #1 was strongly associated with prolonged recovery time (P = 0.0032).
conclusionsSystematic evaluation of exercise tolerance using the BCTT within 1 week after SRC did not affect recovery. The degree of early exercise intolerance after SRC was important for prognosis. This has implications for school academic and team preparation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.