Evidence map›Paper›PMID 29257113›Full record

ReviewSensors (Basel, Switzerland)2017

Sensors and Biosensors for C-Reactive Protein, Temperature and pH, and Their Applications for Monitoring Wound Healing: A Review.

Pietro Salvo, Valentina Dini, Arno Kirchhain, Agata Janowska, Teresa Oranges, Andrea Chiricozzi, Tommaso Lomonaco, Fabio Di Francesco, Marco Romanelli

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
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  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pietro SalvoInstitute of Clinical Physiology, National Council of Research (IFC-CNR), Via Moruzzi 1, 56124 Pisa, Italy. pietro.salvo@gmail.com.ORCID 0000-0003-3866-2993
Valentina DiniDepartment of Dermatology, University of Pisa, Via Roma 67, 56126 Pisa, Italy. valentina.dini@unipi.it.
Arno KirchhainDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Moruzzi 13, 56124 Pisa, Italy. a.kirchhain@studenti.unipi.it.
Agata JanowskaDepartment of Dermatology, University of Pisa, Via Roma 67, 56126 Pisa, Italy. dottoressajanowska@gmail.com.
Teresa OrangesDepartment of Dermatology, University of Pisa, Via Roma 67, 56126 Pisa, Italy. teresa.oranges@gmail.com.
Andrea ChiricozziDepartment of Dermatology, University of Pisa, Via Roma 67, 56126 Pisa, Italy. chiricozziandrea@gmail.com.ORCID 0000-0002-6739-0387
Tommaso LomonacoDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Moruzzi 13, 56124 Pisa, Italy. tommaso.lomonaco@unipi.it.ORCID 0000-0002-1822-7399
Fabio Di FrancescoDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Moruzzi 13, 56124 Pisa, Italy. fabio.difrancesco@unipi.it.
Marco RomanelliDepartment of Dermatology, University of Pisa, Via Roma 67, 56126 Pisa, Italy. m.romanelli@med.unipi.it.ORCID 0000-0002-4127-0141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound assessment is usually performed in hospitals or specialized labs. However, since patients spend most of their time at home, a remote real time wound monitoring would help providing a better care and improving the healing rate. This review describes the advances in sensors and biosensors for monitoring the concentration of C-reactive protein (CRP), temperature and pH in wounds. These three parameters can be used as qualitative biomarkers to assess the wound status and the effectiveness of therapy. CRP biosensors can be classified in: (a) field effect transistors, (b) optical immunosensors based on surface plasmon resonance, total internal reflection, fluorescence and chemiluminescence, (c) electrochemical sensors based on potentiometry, amperometry, and electrochemical impedance, and (d) piezoresistive sensors, such as quartz crystal microbalances and microcantilevers. The last section reports the most recent developments for wearable non-invasive temperature and pH sensors suitable for wound monitoring.

Indexed as

Biosensing TechniquesC-Reactive ProteinHumansSurface Plasmon ResonanceTemperatureWound HealingC-Reactive ProteinbiosensorsC-reactive proteinpHsensorstemperaturewound healing

Identifiers

PMID29257113
PMCPMC5750823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.