Evidence map›Paper›PMID 29256860›Full record

ArticleeLife2017

The zinc-finger transcription factor Hindsight regulates ovulation competency of

Lylah D Deady, Wei Li, Jianjun Sun

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Finishing the egg.Genetics · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. A platform utilizingProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. A Functional Analysis of theG3 (Bethesda, Md.) · 2020
    Article
  14. Dissection of the Ovulatory Process UsingFrontiers in cell and developmental biology · 2020
    Review
  15. Frontiers in endocrinology · 2020
    Article
  16. Downregulation of homeodomain protein Cut is essential forDevelopment (Cambridge, England) · 2019
    Article
  17. NADPH oxidase-generated reactive oxygen species in mature follicles are essential forProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Bio-protocol · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lylah D DeadyDepartment of Physiology and Neurobiology, University of Connecticut, Connecticut, United States.ORCID http://orcid.org/0000-0002-9316-1326
Wei LiDepartment of Physiology and Neurobiology, University of Connecticut, Connecticut, United States.ORCID http://orcid.org/0000-0001-8699-5325
Jianjun SunDepartment of Physiology and Neurobiology, University of Connecticut, Connecticut, United States.ORCID http://orcid.org/0000-0002-6015-738X
University of Connecticut · US

Funding

Genetic interrogation of conserved follicular factors for matrix metalloproteinase regulation and ovulationR01HD086175 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2016 to 2020
$1.7M
Leica TCS SP8 FSU AOBS 405 UV Spectral Confocal MicroscopeS10OD016435 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2014 to 2014
$456k
NICHD NIH HHS R01 HD086175NIH HHS S10 OD016435
6 · The paper itself

Abstract

Follicle rupture, the final step in ovulation, utilizes conserved molecular mechanisms including matrix metalloproteinases (Mmps), steroid signaling, and adrenergic signaling. It is still unknown how follicles become competent for follicle rupture/ovulation. Here, we identify a zinc-finger transcription factor Hindsight (Hnt) as the first transcription factor regulating follicle's competency for ovulation in

Indexed as

Gene Expression RegulationOvulationAnimalsDrosophilaDrosophila ProteinsGenetic Complementation TestHumansMatrix Metalloproteinase 2Nuclear ProteinsReceptors, NeurotransmitterTranscription FactorsDrosophila ProteinsMatrix Metalloproteinase 2Nuclear ProteinsOAMB protein, Drosophilapeb protein, DrosophilaReceptors, NeurotransmitterTranscription Factorsdevelopmental biologyD. melanogasterfollicle maturationHindsightMmp2OambovulationRREB-1stem cells

Identifiers

PMID29256860
PMCPMC5768419
OpenAlexW2781468981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.