Evidence map›Paper›PMID 29255963›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2018

When aphasia is due to aphasic status epilepticus: a diagnostic challenge.

Sonia Quintas, Juan Camilo Ródriguez-Carrillo, Rafael Toledano, María de Toledo, Francisco José Navacerrada Barrero, M Álvaro Berbís, Ana Beatriz Gago-Veiga

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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  7. Adult-onset epileptic aphasia.BMJ case reports · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sonia QuintasDepartment of Neurology, Hospital Universitario de la Princesa, Calle Diego de León, 62, 28006, Madrid, Spain. sonia.qg@gmail.com.ORCID http://orcid.org/0000-0003-0622-8228
Juan Camilo Ródriguez-CarrilloDepartment of Neurology, Hospital Universitario de la Princesa, Calle Diego de León, 62, 28006, Madrid, Spain.
Rafael ToledanoEpilepsy Unit, Department of Neurology, Hospital Ruber Internacional, Madrid, Spain.
María de ToledoDepartment of Neurology, Hospital Universitario de la Princesa, Calle Diego de León, 62, 28006, Madrid, Spain.
Francisco José Navacerrada BarreroHospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain.
M Álvaro BerbísHealth Time, Córdoba, Spain.
Ana Beatriz Gago-VeigaDepartment of Neurology, Hospital Universitario de la Princesa, Calle Diego de León, 62, 28006, Madrid, Spain.
Hospital Universitario de La Princesa · ESHospital Ruber Internacional · ESHospital Universitario Infanta Sofía · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aphasic status epilepticus is an uncommon entity that should be included in the differential diagnosis of persistent and sudden language disorders. In our study, we describe seven patients admitted with clinical and electroencephalographic diagnosis of aphasic status, who were studied with both neuroimaging and electroencephalogram. The mean age was 65.9 years (range of 39-89). Three of the patients had previously been diagnosed of epilepsy. The aphasia was global in six patients. In one case, we found foci of the left hemorrhagic contusions. The initial electroencephalogram (EEG) was not conclusive of status in two patients. In one patient, neuroimaging showed left hemispheric hypoperfusion, compatible with postictal changes. Six out of seven patients required at least two antiepileptic drugs. Three patients died of systemic complications (infectious causes), whereas the other four cases had a complete recovery. Our study highlights that a second EEG study might be necessary to confirm epileptiform activity, when clinical features and other tests suggest an epileptic origin. An early and specific treatment, avoiding or diminishing comorbidities, might significantly improve the prognosis of these patients.

Indexed as

AdultAgedAged, 80 and overAnticonvulsantsAphasiaDiagnosis, DifferentialElectroencephalographyEpilepsyFemaleHumansMaleMiddle AgedNeuroimagingSeizuresStatus EpilepticusAnticonvulsantsAphasiaDiagnosisElectroencephalogramPrognosisStatus

Identifiers

PMID29255963
OpenAlexW2778559612

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.