Evidence map›Paper›PMID 29255745›Full record

ArticleGE Portuguese journal of gastroenterology2017

Diagnostic Accuracy of Controlled Attenuation Parameter for Detecting Hepatic Steatosis in Patients with Chronic Liver Disease.

Patrícia Andrade, Susana Rodrigues, Eduardo Rodrigues-Pinto, Rui Gaspar, Joanne Lopes, Susana Lopes, Guilherme Macedo

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Article in GE Portuguese journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. [Analysis of the clinical value of ultrasound attenuation parameters in evaluating liver steatosis degree in patients with chronic liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrícia AndradeDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Susana RodriguesDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Eduardo Rodrigues-PintoDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Rui GasparDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Joanne LopesDepartment of Pathology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Susana LopesDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.
Guilherme MacedoDepartment of Gastroenterology, Faculty of Medicine, Centro Hospitalar São João, University of Porto, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionControlled attenuation parameter (CAP), measured by transient elastography, has been suggested as a noninvasive method for the detection and quantification of steatosis. We aimed to assess the accuracy of CAP to detect steatosis in patients with chronic liver disease (CLD) compared with liver histology and to evaluate factors that correlate with the CAP value.

methodsPatients with CLD who underwent liver biopsy and simultaneous CAP determination were consecutively enrolled. CAP was measured using the M probe of FibroScan® (Echosens, Paris, France). Histologically, steatosis was categorized as absent (S0: <5%), mild (S1: 5-33%), moderate (S2: 34-66%) and severe (S3: >66% of all hepatocytes).

resultsWe analyzed 159 patients with CLD (61% men, mean age 47.9 ± 12.9 years). We found a positive correlation between CAP and steatosis in histology (

conclusionsCAP had an excellent diagnostic accuracy for the detection of steatosis in diverse CLD patients. A CAP value cutoff of <282.5 dB/m excludes severe steatosis ≥S3 with an accuracy of 98%.

Indexed as

Chronic liver diseaseControlled attenuation parameterLiver biopsySteatosisTransient elastography

Identifiers

PMID29255745
PMCPMC5729946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.