Evidence map›Paper›PMID 29255739›Full record

ArticleOpen forum infectious diseases2017

Extended Screening Costs Associated With Selecting Donors for Fecal Microbiota Transplantation for Treatment of Metabolic Syndrome-Associated Diseases.

Laura J Craven, Seema Nair Parvathy, Justin Tat-Ko, Jeremy P Burton, Michael S Silverman

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05790356 (Fecal Microbial Transplantation for Rheumatoid Arthritis Trial), which is not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05790356 narecruitingnot on this mapstarted 2023, after this paper: background citation

Fecal Microbial Transplantation for Rheumatoid Arthritis Trial

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2023 to 2026Enrolled30ConditionsArthritis, Arthritis, Rheumatoid, Fecal Microbiota TransplantationArmsFecal Microbial transplant, Placebo capsules
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Transient colonization with Blastocystis spp. after transmission via fecal microbiota transplantation.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Microbiome Therapeutics for Clostridioides difficile Infection.Infectious disease clinics of North America · 2025
    Review
  8. Review
  9. Article
  10. Microbes as medicine.Annals of the New York Academy of Sciences · 2024
    Review
  11. Review
  12. Review
  13. High carriage rate of extended-spectrum β-lactamase Enterobacterales and diarrheagenic Escherichia coli in healthy donor screening for fecal microbiota transplantation.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura J CravenDepartment of Microbiology and Immunology, London, Ontario, Canada.
Seema Nair ParvathyDepartment of Infectious Disease, St. Joseph's Health Care, London, Ontario, Canada.
Justin Tat-KoDepartment of Microbiology and Immunology, London, Ontario, Canada.
Jeremy P BurtonDepartment of Microbiology and Immunology, London, Ontario, Canada.
Michael S SilvermanDepartment of Microbiology and Immunology, London, Ontario, Canada.
Western University · CASt Joseph's Health Care · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge of the impact of the gut microbiome on conditions other than

methodsForty-six potential donors (PDs) had their medical histories and physical examinations undertaken by a physician. Blood, stool, and urine were screened for 31 viral, bacterial, fungal, and protozoan agents in addition to biochemical characteristics. The price of advertising, doctor's visits and diagnostic tests were calculated to determine the cost of finding a donor.

resultsOf the PDs screened, 5 of 46 passed the history, examination, blood, stool, and urine tests. The most common reasons for exclusion included a body mass index >25 or the detection of

conclusionsNew potential therapeutic uses for FMT have created a demand for stricter exclusion criteria for donors. This study illustrates that screening many individuals to find a donor and the subsequent associated costs may make central processing and shipment a more reasonable alternative.

Indexed as

fecal microbiota transplantmetabolic syndromestool bank

Identifiers

PMID29255739
PMCPMC5730934
OpenAlexW2767577469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.